| 100% | TREK | 4 | --> ____" (sci-fi franchise) |
| 100% | WARS | 4 | --> ____" (sci-fi franchise) |
| 100% | STARWARS | 8 | Mega sci fi movie franchise began in 1977 |
| 99% | STARTREK | 8 | Sci-fi franchise |
| 91% | TERMINATOR | 10 | Sci-fi franchise since 1984 |
| 91% | ALIEN | 5 | Sci-fi franchise since 1979 |
| 90% | TRON | 4 | Sci-fi franchise with "light cycles" |
| 90% | APES | 4 | Sci-fi franchise "Planet of the ___" |
| 88% | TRON | 4 | Jeff Bridges sci-fi franchise |
| 86% | ALIEN | 5 | James Cameron's sci-fi franchise |
| 86% | STAR | 4 | With 24 Down, sci-fi franchise |
| 86% | WARS | 4 | "Star ___," George Lucas sci-fi franchise |
| 85% | DUNE | 4 | Sci-fi franchise based on a Frank Herbert novel |
| 85% | HALO | 4 | Sci-fi franchise that started as an Xbox game |
| 84% | APES | 4 | Simians in a popular sci-fi franchise |
| 84% | STARTREK | 8 | American sci-fi franchise including Mr. Spock |
| 84% | STAR | 4 | "___ Wars" sci-fi movie franchise |
| 83% | STARTREK | 8 | Sci-fi franchise featuring 39-Across as Spock (2 wds.) |
| 83% | TRON | 4 | Sci-fi franchise that inspired a Magic Kingdom “Lightcycle” ride |
| 83% | TRON | 4 | Sci-fi franchise whose upcoming third film is subtitled "Ares" |
| 83% | HALO | 4 | Sci-fi video game franchise with militaristic aliens |
| 83% | HALO | 4 | Sci-fi first-person shooter video game franchise |
| 83% | TREK | 4 | Shorthand for Gene Roddenberry's sci-fi franchise |
| 83% | DUNE | 4 | "Fear is the mind-killer" sci-fi franchise |
| 83% | JEDI | 4 | Lightsaber wielder, in a famous sci-fi franchise |
| 83% | HALO | 4 | Military-themed sci-fi franchise in video games |
| 82% | HALO | 4 | Microsoft sci-fi video game franchise |
| 81% | THEMATRIX | 9 | Sci-fi movie franchise starring Keanu Reeves: 2 wds. |
| 81% | STAR | 4 | * "___ Wars," sci-fi franchise that features beings like 11a |
| 80% | BACK | 4 | "___ to the Future," sci-fi film franchise |