| 100% | BAUTISTA | 8 | “Guardians of the Galaxy” co-star Dave |
| 76% | DRAX | 4 | The Guardian of the Galaxy played by Dave Bautista |
| 71% | DJIMONHOUNSOU | 13 | "Guardians of the Galaxy" actor and co-star of Leonardo DiCaprio in "Blood Diamond" (2 wds.) |
| 71% | JEDI | 4 | Guardians of the "Star Wars" galaxy |
| 71% | PRATT | 5 | "Guardians of the Galaxy" star Chris |
| 67% | ZOE | 3 | Guardians of the Galaxy actor Saldana |
| 66% | RACCOON | 7 | Rocket __; Guardians of the Galaxy marksman |
| 65% | STARLORD | 8 | Guardian of the Galaxy played by Chris Pratt (Hyph.) |
| 64% | VINDIESEL | 9 | He plays Groot in Guardians of the Galaxy |
| 64% | ROCKET | 6 | Raccoon in Marvel's Guardian of the Galaxy |
| 64% | EGO | 3 | Sentient planet from "Guardians of the Galaxy" who is the biological father of Star-Lord |
| 63% | RACOON | 6 | Rocket is this animal in Guardians of the Galaxy |
| 59% | PRATT | 5 | Chris ___, star of "Guardians of the Galaxy" |
| 59% | PRATT | 5 | Chris —, US actor who played Peter Quill in 2014 action film Guardians of the Galaxy |
| 59% | CHRIS | 5 | & 16D US actor who plays Peter Quill in 2014 action film Guardians of the Galaxy |
| 59% | ALIEN | 5 | "Guardians of the Galaxy" figure |
| 59% | GROOT | 5 | "Guardians of the Galaxy" hero |
| 59% | ROCKET | 6 | "Guardians of the Galaxy" raccoon |
| 58% | DIESEL | 6 | "Guardians of the Galaxy" actor Vin |
| 58% | PACE | 4 | "Guardians of the Galaxy" actor Lee |
| 58% | ZOE | 3 | "Guardians of the Galaxy" actress Saldana |
| 58% | PRATT | 5 | "Guardians of the Galaxy" actor Chris ___ |
| 58% | LEE | 3 | "Guardians of the Galaxy" actor ___ Pace |
| 58% | GUNN | 4 | "Guardians of the Galaxy" filmmaker James |
| 58% | RACCOON | 7 | "Guardians of the Galaxy" character Rocket ___ |
| 58% | GUNN | 4 | “Guardians of the Galaxy” director James |
| 57% | CHRIS | 5 | With 33-Across, "Guardians of the Galaxy" star who plays Owen Grady in 15-/49-Across |
| 57% | ETS | 3 | "Guardians of the Galaxy" title characters, informally |
| 57% | ETS | 3 | Many "Guardians of the Galaxy" characters |
| 57% | TREE | 4 | Plant that Groot resembles, in "The Guardians of the Galaxy" |