| 100% | AANDE | 5 | “The First 48” network |
| 95% | AANDE | 5 | "The First 48" network (3 wds.) |
| 73% | TNT | 3 | "Murder in the First" network |
| 71% | EMERIL | 6 | First name on the Food Network |
| 69% | RCA | 3 | Creator of the first radio network |
| 68% | JOHNBELUSHI | 11 | Star of the first four seasons of 48-Down: 2 wds. |
| 68% | FACEBOOKBUTTONS | 15 | What the first words in 17-, 29- and 48-Across are |
| 68% | CHARLESKURALT | 13 | Journalist who was the first host of 48-Across (2 wds.) |
| 66% | MTV | 3 | Network whose first video was "Video Killed the Radio Star" |
| 64% | TBS | 3 | Network descended from the first national "superstation" |
| 64% | DOG | 3 | Word that can follow the first parts of 19-, 32-, 40- and 48-Across |
| 64% | CSPAN | 5 | First network to broadcast a live session of the House of Representatives |
| 62% | ERODED | 6 | Eaten away, like the first words of 17-, 31-, 48- and 65-Across in order? |
| 62% | JAMESBOND | 9 | British spy played by 33-Across for the first time in 48-Across (2 wds.) |
| 62% | CURLINGBONSPIEL | 15 | Athletic tournament hinted at by the first words in 17-, 23-, 48-, and 60-Across |
| 61% | ANN | 3 | ___ Compton, first woman to cover the White House for a TV network |
| 60% | SPIKETV | 7 | "The first network for men" sloganeer, once |
| 60% | SYNS | 4 | Roget offerings (abbr.) ... or, loosely, the first and last words of 20-, 28-, 48- and 56-Across |
| 59% | ONE | 3 | The first |
| 59% | JOAN | 4 | ___ Rivers, comedian and actress who was the first woman to host a late-night network TV talk show |
| 58% | ADAM | 4 | The first man |
| 58% | TIC | 3 | The first X? |
| 58% | DEL | 3 | The first st. |
| 58% | DE | 2 | The First State |
| 58% | ORIG | 4 | The first: Abbr. |
| 58% | EVE | 3 | The first lady? |
| 58% | EDEN | 4 | The first place |
| 58% | ATOB | 4 | The first step |
| 58% | ONE | 3 | The first numeral |
| 58% | EVE | 3 | The first woman |