| 100% | MEDIAN | 6 | 15 in the set {4, 8, 15, 16, 23} |
| 67% | LOST | 4 | Former ABC drama that involved the number sequence 4, 8, 15, 16, 23, 42 |
| 47% | PERIODDRAMAS | 12 | Works set in the 16-Across |
| 46% | MEAN | 4 | 5, for the set {2, 4, 6, 8} |
| 46% | MEAN | 4 | 5, for the set [2, 4, 6, 8] |
| 43% | WINTERSBONE | 11 | 2010 film set in the Ozarks for which 15-/48-Across received an Oscar nomination: 2 wds. |
| 42% | WINTERSBONE | 11 | 2010 film set in the Ozarks for which 15-/48-Across received her first Oscar nomination: 2 wds. |
| 42% | GREENWING | 9 | 2000s Channel 4 television comedy series set in the fictional East Hampton Hospital Trust |
| 40% | COMICBOOK | 9 | Setting for each of the places in 15-, 21-, and 41-Across: 2 wds. |
| 40% | REVERSE | 7 | What the numbers 9, 8, 7, 6, 5, 4, 3, 2 and 1 are in |
| 40% | AFEWGOODMEN | 11 | 1992 movie in which 15-Across says "You can't handle the truth!": 4 wds. |
| 40% | FORK | 4 | With 15-Across, utensil usually at the far left in a place setting |
| 39% | CONSTELLATION | 13 | Star pattern in the night sky such as 15-Across, 20-Across, 23-Across, 39-Across, and 42-Across |
| 38% | ONEALL | 6 | Score early in the set, maybe |
| 38% | ODDSANDENDS | 11 | Miscellany ... or a description of the final words in 15-, 23-, 30-, 38- and 43-Across |
| 38% | HATH | 4 | 8-Down, in the Bible |
| 38% | TEATIME | 7 | 4:00 in the afternoon |
| 38% | RIB | 3 | 4-Down in the chest |
| 38% | ORIENT | 6 | Set in the right direction |
| 38% | GMT | 3 | Setting in the U.K.? |
| 37% | BAKE | 4 | (4/5) In a preheated oven, ___ (cook) the dough for about 15 minutes. |
| 37% | PACE | 4 | Set the ___ (be in the lead) |
| 37% | ENOLAGAY | 8 | Plane in the news, 8/45 |
| 37% | ESTATE | 6 | Set tea out in the grounds |
| 37% | NAM | 3 | Setting in the film "Tropic Thunder" |
| 37% | MISLAYS | 7 | Sets down in the wrong place |
| 36% | OPENS | 5 | The store ___ at 8 in the morning |
| 36% | BRAT | 4 | 4-Down, in the eyes of many |
| 36% | CAMP | 4 | Set up a tent in the woods |
| 36% | EAU | 3 | Liquid in the 8-Down |