| 100% | STANLEYTUCCI | 12 | 19-Across and 32-Across actor who plays Dr. Abraham Erskine in "Captain America: The First Avenger" (2 wds.) |
| 51% | PETERSELLERS | 12 | Actor who played Pres. Merkin Muffley, Group Capt. Lionel Mandrake, and the title character in 32-Across: 2 wds. |
| 51% | EWANMCGREGOR | 12 | Actor who played 29-/32-Across in the 1990s and 2000s: 2 wds. |
| 51% | ALECGUINNESS | 12 | Actor who played 29-/32-Across in the 1970s and 1980s: 2 wds. |
| 50% | KELSEYGRAMMER | 13 | Actor who played Dr. Frasier Crane in "Frasier" and "Cheers", and hosted the 1998 Grammy Awards: 2 wds. |
| 50% | CHRISEVANS | 10 | Actor who's played both Captain America and the Human Torch: 2 wds. |
| 49% | KEVINALEJANDRO | 14 | "Lucifer" actor who plays Captain Manny Perez in 19-Across: 2 wds. |
| 49% | MADSMIKKELSEN | 13 | "Hannibal" actor who plays the villain Kaecilius in 32-Across: 2 wds. |
| 49% | EVANS | 5 | Chris —, US actor who played the title role in 2011 action film Captain America: The First Avenger |
| 49% | REDSKULL | 8 | Villain who recovered the Tesseract in "Captain America: The First Avenger": 2 wds. |
| 49% | HENRYFONDA | 10 | "On Golden Pond" actor who played the title role in 32-Across: 2 wds. |
| 48% | JOSHOCONNOR | 11 | "Emma" actor who played 32-Across in seasons 3 and 4 of "The Crown": 2 wds. |
| 48% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 48% | REBBROWN | 8 | Actor who played the titular character in the TV movie "Captain America" in 1979: 2 wds. |
| 47% | SEBASTIANSTAN | 13 | "Avengers: Endgame" actor who plays the Winter Soldier in "The Falcon and the Winter Soldier": 2 wds. |
| 47% | EDDIEMURPHY | 11 | "Coming to America" actor who played the title role in 1998's "Dr. Dolittle": 2 wds. |
| 47% | FREDRICMARCH | 12 | Actor who played the lawyer based on William Jennings Bryan in 32-Across: 2 wds. |
| 46% | PAULSCHNEIDER | 13 | Actor who played the role of Mark Brendanawicz in "Parks and Recreation", a character that appeared only in the first two seasons: 2 wds. |
| 46% | ELIJAHWOOD | 10 | "The Lord of the Rings" actor who plays Fritz Garbinger in the 2025 movie "The Toxic Avenger": 2 wds. |
| 46% | FREDSAVAGE | 10 | Actor who played Kevin Arnold on the original 32-Across and who directed the first episode of the 2021 reboot of 32-Across (2 wds.) |
| 46% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 46% | SHAWNHATOSY | 11 | "In & Out" actor who plays the son Andrew "Pope" Cody in 32-Across: 2 wds. |
| 46% | ANTHONYMACKIE | 13 | "Avengers: Endgame" actor who plays Falcon in "The Falcon and the Winter Soldier": 2 wds. |
| 46% | FREDSAVAGE | 10 | Actor who played Kevin Arnold in the original version of 36-Across and is coproducing the reboot: 2 wds. |
| 46% | GREGORYPECK | 11 | Actor who plays Abraham Lincoln in the 1982 TV miniseries "The Blue and the Gray" (2 wds.) |
| 46% | PETERDINKLAGE | 13 | "Game of Thrones" actor who plays the title character in "The Toxic Avenger": 2 wds. |
| 46% | JUDELAW | 7 | "Alfie" actor who played Dr. Watson in the movie "Sherlock Holmes": 2 wds. |
| 46% | DWAYNEJOHNSON | 13 | "Hobbs & Shaw" actor who plays riverboat captain Frank in the 2021 film "Jungle Cruise": 2 wds. |
| 45% | NICKOFFERMAN | 12 | "Parks and Recreation" actor who plays the US president in "Civil War": 2 wds. |
| 45% | CHRISEVANS | 10 | Actor who plays Captain America in "Avengers: Endgame" (2 wds.) |