| 100% | PIRATES | 7 | 1986 adventure-comedy film starring Walter Matthau as Captain Thomas Bartholomew Red |
| 53% | PIRATES | 7 | 1986 adventure-comedy film starring Walter Matthau and Cris Campion |
| 39% | THEFRONTPAGE | 12 | Billy Wilder film starring Walter Matthau as a newspaper editor and Jack Lemmon as a reporter (3 wds.) |
| 38% | GRUMPYOLDMEN | 12 | Donald Petrie film starring Walter Matthau and Jack Lemmon as feuding next-door neighbors (3 wds.) |
| 38% | THEODDCOUPLE | 12 | Gene Saks film starring Walter Matthau and Jack Lemmon as mismatched roommates Oscar and Felix (3 wds.) |
| 36% | KOTCH | 5 | 1971 comedy-drama film starring Walter Matthau in the title role |
| 35% | GOONIES | 7 | "The ___," 1985 adventure comedy film starring Sean Astin, Josh Brolin, and an ensemble cast as a group of kids living in the "Goon Docks" |
| 35% | THREEAMIGOS | 11 | 1986 American Western comedy film starring Steve Martin as Lucky Day: 2 wds. |
| 34% | MANHUNTER | 9 | 1986 film thriller starring William Petersen based on the Thomas Harris novel Red Dragon |
| 34% | THEBADNEWS | 10 | & 12D 1976 comedy-drama film starring Walter Matthau and Tatum O’Neal |
| 33% | ZOOM | 4 | 2006 adventure comedy film starring Tim Allen and Courteney Cox |
| 33% | GOONIES | 7 | "The ___," 1985 adventure comedy film starring Sean Astin and Josh Brolin |
| 32% | GRUMPYOLDMEN | 12 | 1993 comedy-drama film starring Jack Lemmon and Walter Matthau |
| 32% | BLOCKERS | 8 | Comedy film starring 27-Down as an overprotective father |
| 31% | ZOOLANDER | 9 | 2001 fashion comedy film starring Ben Stiller and Will Ferrell as "Mugatu" |
| 30% | ANALYZETHIS | 11 | Comedy film starring 42-Across as psychiatrist who treats a mob boss (2 wds.) |
| 30% | CIRCUS | 6 | "The ___," 1928 comedy film starring Charlie Chaplin's Little Tramp as a clown |
| 30% | BLOCKERS | 8 | 2018 comedy film starring 27-Down as an over-protective father |
| 30% | NIGHTSCHOOL | 11 | Comedy film starring 15-Across and 45-Across as dropouts working toward a GED (2 wds.) |
| 30% | BYEBYEBIRDIE | 12 | 1963 musical comedy film starring Dick Van Dyke as songwriter Albert Peterson: 3 wds. |
| 29% | BADNEWSBEARS | 12 | Sports comedy film starring Billy Bob Thornton as a Little League baseball coach (3 wds.) |
| 29% | BLADESOFGLORY | 13 | Sports comedy film starring Will Ferrell and Jon Heder as Olympic ice skaters (3 wds.) |
| 29% | BLADESOFGLORY | 13 | Sports comedy film starring Will Ferrell and Jon Heder as professional ice skaters (3 wds.) |
| 29% | FRONTPAGE | 9 | The —, 1974 comedy-drama film starring Jack Lemmon and Walter Matthau |
| 29% | WALK | 4 | "___, Don't Run," comedy film by Charles Walters starring Cary Grant |
| 29% | COOL | 4 | "Stay ___," 2011 comedy film which stars Winona Ryder as Scarlet Smith |
| 29% | CLOCKWISE | 9 | 1986 film comedy starring John Cleese and Penelope Wilton |
| 29% | BADGUYS | 7 | 1986 film comedy starring Adam Baldwin and Mike Jolly |