| 100% | QUANTUMLEAP | 11 | 1989 American sci-fi series about a physicist who leaps through spacetime to correct historical mistakes: 2 wds. |
| 35% | MISSIONTO | 9 | "___ Mars," American sci-fi film from 2000 about a manned exploration mission to Mars that goes wrong: 2 wds. |
| 35% | SMALLWONDER | 11 | 1985 American sci-fi sitcom about the family of an engineer who creates a human girl-robot Vicki: 2 wds. |
| 30% | STAR | 4 | "The Powers of Matthew ___," 1982 American sci-fi series about the adventures of a high-school student who is actually a powerful alien |
| 29% | MALIBUCOUNTRY | 13 | Sitcom about a divorced mom who relocates to California: 2 wds. |
| 28% | EMILYINPARIS | 12 | Netflix series about an American woman who moves to France starring 14-Across and 29-Across (3 wds.) |
| 28% | LOSESPOOKYS | 11 | HBO comedy about a group of Latin American friends trying to build a horror business: 2 wds. |
| 27% | UNCLEBUCK | 9 | 1989 comedy about a slob who acts as a babysitter for his nieces and nephew: 2 wds. |
| 27% | DEARPRUDENCE | 12 | Beatles song about a girl who is invited to "come out to play": 2 wds. |
| 27% | FREEWILLY | 9 | 1993 film about a boy who tries to rescue a killer whale from an unscrupulous aquarium: 2 wds. |
| 27% | HARPERSISLAND | 13 | American horror mystery series that follows a group who travel for a destination wedding: 2 wds. |
| 27% | ENDER | 5 | Sci-fi character who's trained through a series of war games |
| 27% | RED | 3 | 1988 British sci-fi comedy series about the adventures of the last human alive stranded on a mining spaceship: 2 wds. |
| 26% | SMALLWONDER | 11 | 1985 American science fiction comedy about a small girl who is a robot starring Tiffany Brissette: 2 wds. |
| 26% | THEALCHEMIST | 12 | Paulo Coelho novel about a boy who travels to find a treasure at the Egyptian pyramids: 2 wds. |
| 26% | WOLFHALL | 8 | Historical drama series about the rise to power of Thomas Cromwell in the court of Henry VIII: 2 wds. |
| 26% | ORK | 3 | Planet in the 1978 American sci-fi sitcom "Mork & Mindy" about an extraterrerstrial who comes to Earth |
| 26% | LASTSONG | 8 | Novel by Nicholas Sparks about a 17 year old teen who is sent to stay with her father in the summer, "The ___": 2 wds. |
| 26% | FIRECOUNTRY | 11 | CBS drama about a prison inmate who volunteers to fight blazes: 2 wds. |
| 26% | BOJACKHORSEMAN | 14 | Netflix animated series about a washed-up sitcom star: 2 wds. |
| 26% | SILICONVALLEY | 13 | Comedy series about a high-tech start-up company: 2 wds. |
| 25% | PSYCH | 5 | TV series about a detective who pretended to have ESP |
| 25% | LIVINGWITH | 10 | With 28-Across, Netflix series about a man and his clone: 2 wds. |
| 25% | MONEYHEIST | 10 | Spanish language series about a criminal mastermind known as "The Professor": 2 wds. |
| 25% | THEBOYS | 7 | TV series about vigilantes who fight superheroes: 2 wds. |
| 25% | KNIGHTRIDER | 11 | 1982 American TV series about a crime fighter and an intelligent car starring David Hasselhoff: 2 wds. |
| 25% | NNEDIOKORAFOR | 13 | African-American sci-fi novelist who won a Hugo Award and a Nebula Award for Best Novella (2 wds.) |
| 24% | PSYCH | 5 | Former TV series about a detective who pretended to have ESP |
| 24% | CATS | 4 | "Thunder___," animated series about a group of feline humanoid aliens that ran from 1985 to 1989 |
| 24% | WOLFHALL | 8 | PBS "Masterpiece" series about Thomas Cromwell's rise to power: 2 wds. |