| 100% | ANGELASASHES | 12 | 1996 memoir set in Brooklyn and Ireland (2 wds.) |
| 46% | NASHBRIDGES | 11 | Police procedural set in San Francisco starring 13-Across and 25-Across that began its six-year run in 1996 (2 wds.) |
| 46% | EVESBAYOU | 9 | 1997 film set in Louisiana, starring Lynn Whitfield and Samuel L. Jackson: 2 wds. |
| 45% | RYANSDAUGHTER | 13 | 1970 romantic epic directed by David Lean and set in Ireland: 2 wds. |
| 44% | DERRYGIRLS | 10 | British sitcom set in Northern Ireland that starred 34-Across as Catholic school student Clare Devlin: 2 wds. |
| 43% | DERRYGIRLS | 10 | Sitcom set in Northern Ireland featuring 1990s teenagers (2 wds.) |
| 43% | MYSTICRIVER | 11 | 2003 movie set in Boston, for which Sean Penn and Tim Robbins each won a 1-Across: 2 wds. |
| 43% | ALLTHAT | 7 | "She's ___," 1999 rom-com set in a high school featuring Freddie Prinze Jr. and Rachael Cook: 2 wds. |
| 43% | BLADERUNNER | 11 | 1982 science fiction film set in a dystopian future Los Angeles and about synthetic humans known as replicants: 2 wds. |
| 43% | THECOSBYSHOW | 12 | 1984-1992 NBC sitcom set in Brooklyn: 3 wds. |
| 42% | DUBLINMURDERS | 13 | Crime series set in Ireland based on Tana French novels (2 wds.) |
| 41% | MIAMIVICE | 9 | 1980s police drama set in Florida starring 15-Across and 33-Across (2 wds.) |
| 41% | YOURHONOR | 9 | Showtime miniseries set in New Orleans starring 15-Across and 33-Across (2 wds.) |
| 41% | JACKTAYLOR | 10 | Mystery drama series set in Ireland starring Iain Glen as a private investigator (2 wds.) |
| 41% | DUBLINMURDERS | 13 | BBC/Starz crime series set in Ireland based on novels by Tana French (2 wds.) |
| 40% | OFMAN | 5 | Isle ___, island on a sea between England and Ireland: 2 wds. |
| 40% | MIAMIVICE | 9 | Stylish '80s police drama set in Florida: 2 wds. |
| 40% | ITOO | 4 | "Am ___ set in my ways?": 2 wds. |
| 39% | GREYSANATOMY | 12 | ABC medical drama set in Seattle: 2 wds. |
| 39% | MAGNUMPI | 8 | CBS detective show set in Hawaii: 2 wds. |
| 38% | ASHES | 5 | "Angela's ___" (1996 memoir largely set in Ireland) |
| 38% | DOCTORZHIVAGO | 13 | 1957 novel set in early 20th-century Russia: 2 wds. |
| 38% | MALIBUCOUNTRY | 13 | Sitcom set in Southern California starring Reba McEntire: 2 wds. |
| 38% | DIEHARD | 7 | Action film set in the fictional Nakatomi Plaza: 2 wds. |
| 38% | GROUNDHOGDAY | 12 | 1993 Harold Ramis film set in Punxsutawney, Pennsylvania: 2 wds. |
| 38% | THEGOLDBERGS | 12 | ABC comedy series set in the 1980s: 2 wds. |
| 38% | STRANGERTHINGS | 14 | Netflix horror series set in the 1980s: 2 wds. |
| 38% | THEAMERICANS | 12 | FX spy series set in the 1980s: 2 wds. |
| 38% | EATPRAYLOVE | 11 | Julia Roberts film set in Italy, India, and Indonesia (3 wds.) |
| 38% | STEPHENKING | 11 | "Carrie" author whose stories are usually set in Maine: 2 wds. |