| 100% | MICHAELJFOX | 11 | 2000 Emmy winner, Outstanding Lead Actor in a Comedy Series (for "Spin City"): 3 wds. |
| 72% | ERICMCCORMACK | 13 | 2001 Emmy winner, Outstanding Lead Actor in a Comedy Series (for "Will & Grace"): 2 wds. |
| 68% | JOHNLITHGOW | 11 | 1996, 1997, and 1999 Emmy winner, Outstanding Lead Actor in a Comedy Series (for "3rd Rock From the Sun"): 2 wds. |
| 66% | RAYROMANO | 9 | 2002 Emmy winner for Outstanding Lead Actor in a Comedy Series |
| 66% | JUDDHIRSCH | 10 | 1981 Emmy winner for "Taxi" (Outstanding Lead Actor In a Comedy Series): 2 wds. |
| 65% | DONALDGLOVER | 12 | Emmy winner for Outstanding Lead Actor in a Comedy for "Atlanta": 2 wds. |
| 62% | DAMIANLEWIS | 11 | Winner of the 2012 Emmy for Outstanding Lead Actor in a Drama Series for "Homeland": 2 wds. |
| 62% | JEFFDANIELS | 11 | Winner of the 2013 Emmy for Outstanding Lead Actor in a Drama Series for "The Newsroom": 2 wds. |
| 62% | BRYANCRANSTON | 13 | Winner of the 2014 Emmy for Outstanding Lead Actor in a Drama Series for "Breaking Bad": 2 wds. |
| 59% | JASONSUDEIKIS | 13 | "Ted Lasso" actor who won the 2021 Emmy for Outstanding Lead Actor in a Comedy Series: 2 wds. |
| 59% | EDIE | 4 | 2010 Outstanding Lead Actress in a Comedy Series Emmy winner for Nurse Jackie |
| 58% | EUGENELEVY | 10 | "Schitt's Creek" star who won the 2020 Emmy for Outstanding Lead Actor in a Comedy Series: 2 wds. |
| 58% | EUGENELEVY | 10 | Former SCTV regular who won the 2020 Emmy Award for Outstanding Lead Actor in a Comedy Series for playing Johnny Rose on 46-Across (2 wds.) |
| 57% | NICOLEKIDMAN | 12 | Emmy winner for Outstanding Lead Actress in a Limited Series for "Big Little Lies": 2 wds. |
| 56% | SPIN | 4 | US television sitcom for which Michael J Fox won a 2000 Emmy for Outstanding Lead Actor in a Comedy Series |
| 56% | DONALDGLOVER | 12 | Actor who won the Emmy for Outstanding Lead Actor in a Comedy for "Atlanta": 2 wds. |
| 54% | ELISABETHMOSS | 13 | 2017 Outstanding Lead Actress in a Drama Series Emmy winner for her role on "The Handmaid's Tale" (2 wds.) |
| 54% | ALLISONJANNEY | 13 | "Mom" actress nominated for 2017's Outstanding Lead Actress in a Comedy Series Emmy (2 wds.) |
| 53% | MATTHEWRHYS | 11 | "The Americans" actor nominated for 2017's Outstanding Lead Actor in a Drama Series Emmy (2 wds.) |
| 53% | LIEVSCHREIBER | 13 | "Ray Donovan" actor nominated for 2017's Outstanding Lead Actor in a Drama Series Emmy (2 wds.) |
| 53% | PAMELAADLON | 11 | "Better Things" actress nominated for 2017's Outstanding Lead Actress in a Comedy Series Emmy (2 wds.) |
| 52% | AHMED | 5 | Riz —, 2017 Emmy Award for Outstanding Lead Actor in a Limited Series or Movie winner for The Night Of |
| 52% | LEVY | 4 | Eugene ___, actor from 45a who won the Emmy for Outstanding Lead Actor in a Comedy Series in 2020 |
| 52% | ISSARAE | 7 | "Insecure" star nominated for a 2020 Emmy for Outstanding Lead Actress in a Comedy Series (2 wds.) |
| 52% | JEREMYSTRONG | 12 | "Succession" star who won the 2020 Emmy for Outstanding Lead Actor in a Drama Series: 2 wds. |
| 52% | BOBODENKIRK | 11 | "Better Call Saul" actor nominated for 2017's Outstanding Lead Actor in a Drama Series Emmy (2 wds.) |
| 52% | ELLIEKEMPER | 11 | "Unbreakable Kimmy Schmidt" actress nominated for 2017's Outstanding Lead Actress in a Comedy Series Emmy (2 wds.) |
| 51% | JEANSMART | 9 | "Hacks" star who won an Emmy Award for Outstanding Lead Actress in a Comedy Series in 2022 (2 wds.) |