| 100% | THESURGEON | 10 | 2001 Tess Gerritsen novel about homicide detective Jane Rizzoli, who's hunting a murderer with medical skills: 2 wds. |
| 41% | THEAPPRENTICE | 13 | 2002 Tess Gerritsen novel that introduces medical examiner Maura Isles, who teams up with Rizzoli: 2 wds. |
| 27% | TESSGERRITSEN | 13 | Mystery writer who created Detective Jane Rizzoli and Chief Medical Examiner Maura Isles (2 wds.) |
| 27% | WHATALICE | 9 | With 19-Across, 2009 Liane Moriarty novel about a mother who develops amnesia: 2 wds. |
| 27% | THESTAND | 8 | Stephen King novel about a group of people who survive a worldwide pandemic: 2 wds. |
| 26% | TARBABY | 7 | 1981 Toni Morrison novel about an educated fashion model in love with a poor fugitive: 2 wds. |
| 26% | HOWTOWALKAWAY | 13 | Katherine Center novel about a plane crash survivor who falls in love with her physical therapist (4 wds.) |
| 26% | THEALCHEMIST | 12 | Paulo Coelho novel about a boy who travels to find a treasure at the Egyptian pyramids: 2 wds. |
| 26% | AMILLIONJUNES | 13 | Emily Henry novel about a young woman who finds a connection with the son of her family's enemy when he returns home one summer (3 wds.) |
| 26% | HELLOSTRANGER | 13 | Katherine Center novel about a portrait artist who is diagnosed with face blindness (2 wds.) |
| 26% | THETORNSKIRT | 12 | Novel by 47-Across about a high schooler who becomes obsessed with a homeless girl (3 wds.) |
| 25% | TESSGERRITSEN | 13 | Novelist and former physician whose crime thrillers feature detective Jane Rizzoli and medical examiner Maura Isles (2 wds.) |
| 25% | BABYPROOF | 9 | Emily Giffin novel about a happy couple who argue over having children (2 wds.) |
| 24% | YOUNGJANEYOUNG | 14 | Novel by 44-Across about a political intern who changes her identity when an affair with her boss becomes public (3 wds.) |
| 24% | HAPPYPLACE | 10 | Emily Henry novel about a couple pretending to still be together while vacationing with friends (2 wds.) |
| 24% | BOOKLOVERS | 10 | Emily Henry novel about a literary agent and an editor who meet cute while on vacation (2 wds.) |
| 24% | ASPARKOFLIGHT | 13 | Jodi Picoult novel about a teenager who is held hostage at women's reproductive health clinic (4 wds.) |
| 23% | FLIGHTBEHAVIOR | 14 | 2012 Barbara Kingsolver novel about a colony of butterflies in Tennessee: 2 wds. |
| 23% | VANISHINGACTS | 13 | Jodi Picoult novel about a missing persons investigator who discovers she'd been kidnapped by her father as a child (2 wds.) |
| 22% | FUNNYSTORY | 10 | 2024 romance novel by 44-Across about a librarian who becomes roommates with her ex-fiancé’s new fiancée’s ex (2 wds.) |
| 22% | WHATYOUWISHFOR | 14 | Katherine Center novel about a school librarian and her relationship with the principal (4 wds.) |
| 22% | ANXIOUSPEOPLE | 13 | 2020 best-selling novel about a group held hostage by a bank robber: 2 wds. |
| 22% | ROSEBYRNE | 9 | "Spy" actress who's expecting a second child with her boyfriend Bobby Cannavale: 2 wds. |
| 22% | PETERFALK | 9 | Actor who played a homicide detective in Los Angeles on "Columbo" (2 wds.) |
| 22% | THEBEANTREES | 12 | 1988 Barbara Kingsolver novel about a young woman who cares for an abandoned baby: 3 wds. |
| 22% | AMANCALLEDOVE | 13 | 2014 best-selling novel about a neighborhood curmudgeon who befriends the family next door: 4 wds. |
| 22% | MEANTTOBE | 9 | Emily Giffin novel about a high-profile couple who come from very different backgrounds (3 wds.) |
| 22% | THELITTLELIAR | 13 | Novel by 43-Across about a boy who always tells the truth (3 wds.) |
| 22% | LISTENTOME | 10 | 2022 Tess Gerritsen novel that's the 13th in the book series that spawned the TV show "Rizzoli & Isles": 3 wds. |
| 22% | HERBIEHANCOCK | 13 | Jazz pianist who had a hit with 1983's "Rockit": 2 wds. |