| 100% | CONTAGION | 9 | 2011 movie in which Kate Winslet plays a doctor helping to control a disease outbreak |
| 40% | THEREADER | 9 | 2008 movie in which Kate Winslet plays an illiterate woman: 2 wds. |
| 40% | STEVEJOBS | 9 | 2015 movie in which Kate Winslet plays an Apple marketing executive: 2 wds. |
| 40% | DIVERGENT | 9 | 2014 movie in which Kate Winslet plays the leader of the Erudite faction |
| 39% | MILDREDPIERCE | 13 | 2011 HBO miniseries for which Kate Winslet won an Emmy Award for Outstanding Lead Actress in a Miniseries or Movie (2 wds.) |
| 34% | CONTAGION | 9 | 2011 movie in which Laurence Fishburne played Dr. Ellis Cheever |
| 34% | MOULINROUGE | 11 | Movie in which Nicole Kidman played a prostitute: 2 wds. |
| 34% | PRETTYWOMAN | 11 | Movie in which Julia Roberts played a prostitute: 2 wds. |
| 34% | TAR | 3 | 2022 movie in which Cate Blanchett plays a conductor |
| 34% | TOPGUN | 6 | 1986 movie in which Tom Cruise played a maverick |
| 33% | MISERY | 6 | Movie in which Kathy Bates played a deranged fan of an author |
| 33% | SPY | 3 | 2015 movie in which Melissa McCarthy plays a CIA agent |
| 33% | JUNO | 4 | 2007 movie in which Ellen Page played a pregnant teen |
| 33% | TWISTER | 7 | 1996 movie in which Bill Paxton played a storm chaser |
| 33% | SKY | 3 | "October ___," 1999 movie in which Chris Owen played a math geek |
| 33% | GRACE | 5 | "___ of My Heart," movie in which Ileana Douglas plays a singer-songwriter |
| 32% | DEARJOHN | 8 | 2010 Amanda Seyfried movie in which Channing Tatum played a soldier: 2 wds. |
| 32% | MAN | 3 | "The ___ Who Knew Infinity," 2015 movie in which Dev Patel played a mathematician |
| 32% | WORLDWARZ | 9 | Brad Pitt zombie movie in which Peter Capaldi played a WHO physician: 3 wds. |
| 32% | TOOTSIE | 7 | Movie in which Dustin Hoffman cross-dresses to get a TV role |
| 31% | BRUCEALMIGHTY | 13 | 2003 movie in which 15-Across played a deity: 2 wds. |
| 31% | SHOWBOAT | 8 | 1936 movie musical in which Paul Robeson played a dockworker: 2 wds. |
| 31% | AWRINKLEINTIME | 14 | 2018 fantasy movie in which Reese Witherspoon played a being who flies kids through space: 4 wds. |
| 31% | IRIS | 4 | 2001 film in which Kate Winslet and Judi Dench played the title role |
| 31% | CARE | 4 | "I ___ a Lot," movie in which Eiza Gonzalez plays Rosamund Pike's partner |
| 31% | CONTAGION | 9 | 2011 thriller film starring Kate Winslet which is about a pandemic |
| 31% | TRADINGPLACES | 13 | Movie in which Jamie Lee Curtis played a prostitute: 2 wds. |
| 31% | ASIMPLEPLAN | 11 | 1998 movie in which Bill Paxton played a man who finds money in a crashed plane: 3 wds. |
| 30% | PIXELS | 6 | 2015 fantasy movie about video games in which Josh Gad plays a gaming expert |
| 30% | OTHER | 5 | "Love & ___ Drugs" (2010 film in which Anne Hathaway plays a woman with Parkinson's disease) |