| 100% | THEGOODPLACE | 12 | 2016-2020 NBC comedy featuring Adam Scott as a demon named Trevor: 3 wds. |
| 37% | TODIEFOR | 8 | 1995 black comedy featuring Nicole Kidman as a murderous wife: 3 wds. |
| 36% | APBIO | 5 | NBC comedy named after a high school course: 3 wds. |
| 34% | THEGOODPLACE | 12 | 2016-2020 NBC comedy series about the afterlife costarring 17-Across: 3 wds. |
| 34% | PARTYDOWN | 9 | 2009-2010 Starz sitcom with Adam Scott as a cater-waiter: 2 wds. |
| 33% | BILLYMADISON | 12 | Adam Sandler comedy featuring a cameo by actor Steve Buscemi as the title character's former classmate (2 wds.) |
| 32% | HAPPYGILMORE | 12 | Adam Sandler sports comedy featuring a cameo by director Dennis Dugan as commissioner of the pro golf tour (2 wds.) |
| 31% | SCREAMQUEENS | 12 | 2015-2016 Fox dark comedy featuring Niecy Nash-Betts as a sorority's security guard: 2 wds. |
| 30% | THEREPORT | 9 | 2019 film featuring Adam Driver as a Senate 32-Across (2 wds.) |
| 30% | WAYNESWORLD | 11 | 1992 comedy featuring Rob Lowe as a sleazy TV producer: 2 wds. |
| 29% | HAPPYGILMORE | 12 | 1996 comedy starring Adam Sandler as a hockey player who takes up professional golf: 2 wds. |
| 29% | SATURDAYNIGHT | 13 | "____ Live," a sketch comedy show on NBC, which 40a hosted in 2016: 2 wds. |
| 29% | HORRIBLEBOSSES | 14 | 2011 Jennifer Aniston comedy featuring Jamie Foxx as a "murder consultant": 2 wds. |
| 28% | ABOUTABOY | 9 | Current NBC sitcom starring Minnie Driver as a single mom: 3 wds. |
| 28% | THEGOODPLACE | 12 | NBC comedy that starred Kristen Bell as bisexual character Eleanor Shellstrop: 3 wds. |
| 27% | ISTILLBELIEVE | 13 | 2020 biopic featuring 43-Across named for a hit song by 18-Across (3 wds.) |
| 27% | THEOFFICE | 9 | A comedy which starred Steve Carell as Michael Scott, in which 17-Across played his rival, Charles Miner: 2 wds. |
| 27% | GOINGMYWAY | 10 | 1944 musical featuring Bing Crosby as a young priest who revitalizes a struggling parish: 3 wds. |
| 27% | MYCOUSINVINNY | 13 | 1992 comedy with Joe Pesci as a New York lawyer handling an Alabama trial: 3 wds. |
| 27% | SETHMEYERS | 10 | NBC "Late Night" host whose show was nominated for a 2020 Writers Guild Award for Comedy/Variety Talk Series (2 wds.) |
| 27% | JULIEANDJULIA | 13 | 2009 movie with Amy Adams as a novice cook: 3 wds. |
| 27% | FIELDOFDREAMS | 13 | 1989 film featuring Burt Lancaster as a baseball player whose ghost plays one last game: 3 wds. |
| 26% | THEWAYBACK | 10 | 2020 film starring Ben Affleck as a high school basketball coach: 3 wds. |
| 26% | INTHEBAG | 8 | Virtually certain, as a victory: 3 wds. |
| 26% | SEVERANCE | 9 | 2022-present Apple TV+ dystopian drama starring Adam Scott as a worker in an isolated office |
| 26% | SAUSAGEPARTY | 12 | 2016 animated comedy where Seth Rogen voiced a hot dog named Frank: 2 wds. |
| 26% | THEGREATWALL | 12 | 2016 monster movie with Willem Dafoe as a European adventurer in China: 3 wds. |
| 26% | ATOZ | 4 | NBC comedy starring Ben Feldman and Cristin Milioti: 3 wds. |
| 26% | THENICEGUYS | 11 | A 2016 comedy starring Crowe and Gosling: 3 wds |
| 26% | INLIVINGCOLOR | 13 | 1990s sketch comedy show featuring 45-Across as a member of The Fly Girls dance troupe (3 wds.) |