| 100% | DESPACITO | 9 | 2017 chart-topping hit whose YouTube video was the first to reach 3 billion views |
| 47% | BTS | 3 | Group whose "Butter" video was the fastest to reach 100 million views on YouTube (2021) |
| 45% | BOOMBAYAH | 9 | 2020 51-Across song that was the first K-pop debut music video to pass one billion views on YouTube |
| 43% | BABYSHARK | 9 | Subject of the first YouTube video to reach 10 billion views (2022) |
| 43% | GANGNAMSTYLE | 12 | 2012 Psy hit whose YouTube video has over 3 billion views: 2 wds. |
| 43% | WORKFROMHOME | 12 | 2016 Fifth Harmony hit whose YouTube video has nearly 2 billion views: 3 wds. |
| 40% | KATYPERRY | 9 | "Roar" singer with more than 42 million YouTube subscribers who was the first artist to have multiple music videos reach one billion views on YouTube (2 wds.) |
| 37% | COUNTINGSTARS | 13 | 2013 OneRepublic hit whose YouTube video has over 2 billion views: 2 wds. |
| 37% | DESPACITO | 9 | 2017 hit that was the first Spanish-language song to reach No. 1 on the Billboard Hot 100 since "Macarena" |
| 36% | PSY | 3 | South Korean singer whose hit single "Gangnam Style" went viral becoming the first video on YouTube to exceed one billion views |
| 36% | PSY | 3 | Singer in the first YouTube video to surpass 1 billion views |
| 35% | YOUMIGHTTHINK | 13 | The Cars Top 10 hit whose video features 44-Across as a housefly (and was the first to win the MTV Video Music Award for Video of the Year) (3 wds.) |
| 34% | NORTHPOLE | 9 | Robert Peary was the first to reach this place |
| 34% | PSY | 3 | First music artist to have a video with a billion YouTube views |
| 34% | STILLINTOYOU | 12 | 2013 single that was Paramore's first Top 10 hit on the "Billboard" Mainstream Top 40 chart (3 wds.) |
| 33% | MDA | 3 | Org. whose telethon was the first to be viewed globally via the internet in 1998 |
| 33% | PLEASEMRPLEASE | 14 | 1975 Olivia Newton-John hit whose title's first and last words are the same: 3 wds. |
| 32% | ADELE | 5 | She holds the Guinness record for "fastest time for a video to reach 1 billion views on YouTube" |
| 32% | HARDTOLOVE | 10 | 2012 top 10 hit for Lee Brice (his first on the Hot Country chart): 3 wds. |
| 32% | MOTLEYCRUE | 10 | 1980s hair band whose first Top 20 hit was "Smokin' in the Boys Room" (2 wds.) |
| 32% | JOYTOTHEWORLD | 13 | Popular carol, whose first phrase can be hummed using the circled pitches (from top to bottom) |
| 31% | DESPACITO | 9 | 2017 #1 song whose music video has over 6.5 billion views on YouTube |
| 31% | AJANAOMIKING | 12 | "How to Get Away With Murder" actress whose first name is spelled the same forward and backward: 3 wds. |
| 30% | TITANIC | 7 | The first film to reach the billion-dollar mark |
| 30% | AVATAR | 6 | 2009 movie that was the first film to gross over $2 billion |
| 30% | BIGOLEFREAK | 11 | 2019 Megan Thee Stallion hit that was her first song to make the Billboard charts (3 wds.) |
| 30% | BTS | 3 | K-pop group whose single “Dynamite” broke YouTube’s record for the most first-day views of a music video (August, 2020) |
| 30% | OTT | 3 | Mel who was the first N.L.'er to hit 500 home runs |
| 30% | BRITNEYSPEARS | 13 | Musician whose first single "... Baby one more time" topped the charts in 1998 when she was just 17 years old: 2 wds. |
| 29% | SKYFALL | 7 | 2012 Adele hit that was the first James Bond theme to debut in the top 10 on Billboard's Hot 100 |