| 100% | KAAT | 4 | 25-year pitcher Jim |
| 63% | KAAT | 4 | Longtime baseball pitcher Jim |
| 63% | KAAT | 4 | Former MLB pitcher Jim |
| 63% | BOUTON | 6 | Pitcher Jim |
| 60% | KAAT | 4 | '60s-'70s pitcher Jim |
| 57% | BOUTON | 6 | Pitcher Jim who wrote "Ball Four" |
| 56% | KAAT | 4 | MLB pitcher Jim ___ nicknamed "Kitty" |
| 56% | KAAT | 4 | Hall of Fame pitcher Jim |
| 54% | REUNE | 5 | Meet up in 25 years, maybe |
| 53% | BALL | 4 | "___ Four" (memoir by former pitcher Jim Bouton) |
| 52% | TED | 3 | Koppel who hosted "Nightline" for 25 years |
| 52% | CHIRAC | 6 | Charles de Gaulle successor, 25 years later |
| 52% | KAAT | 4 | Pitcher Jim who was a 16-time Gold Glove winner |
| 51% | AVERAGE | 7 | About 25 years, for N.F.L. players |
| 51% | WEDDING | 7 | *Silver ___ anniversary, occasion marking 25 years of marriage |
| 51% | VERA | 4 | Aloe ___, succulent that can survive for 25 years |
| 51% | THANKSGIVINGDAY | 15 | November 25, this year |
| 48% | ANNALEE | 7 | Late actress who was on "General Hospital" for 25 years |
| 48% | JAMIE | 5 | ___ Moyer, former baseball player whose career spanned over 25 years |
| 48% | MCMIII | 6 | Year of the 21-Acrosses' first 25-Across |
| 47% | MORA | 4 | Jim ___, onetime N.F.L. Coach of the Year |
| 46% | BUNNING | 7 | Hall of Fame pitcher Jim ___, who became a US senator from Kentucky |
| 46% | STOMP | 5 | Show still running at New York's Orpheum Theater after 25 years |
| 46% | XXXXXXXXXXXX | 12 | It's estimated to be a foot in the next 25 years |
| 45% | ROSHHASHANAH | 12 | Jewish New Year, celebrated on Sept. 25, 2022 |
| 44% | NOID | 4 | Reason the bartender might refuse service to a young-looking 25 year old |
| 44% | NOMO | 4 | Pitcher who was the 1995 N.L. Rookie of the Year |
| 44% | HIDEONOMO | 9 | Pitcher who was the 1995 N.L. Rookie of the Year |
| 44% | ARLENEFRANCIS | 13 | She was a regular panelist on 18-Across for 25 years: 2 wds. |
| 44% | SEARS | 5 | Company whose headquarters were the world's tallest building for nearly 25 years |