| 100% | LOVEMEDICINE | 12 | 32-Across's debut novel about folk magic healing relationships (2 wds.) |
| 35% | TIMETRAVELERS | 13 | "The ___ Wife," bestselling debut novel by Audrey Niffenegger published in 2003 about a man who moves through time and his wife: 2 wds. |
| 34% | ABOUTGRACE | 10 | 28-Across's debut novel, which tells the story of a man who dreams events that later come true (2 wds.) |
| 32% | THESURGEON | 10 | 2001 Tess Gerritsen novel about homicide detective Jane Rizzoli, who's hunting a murderer with medical skills: 2 wds. |
| 32% | TANEHISICOATES | 14 | Essayist who published 16-Across as his debut novel: 2 wds., hyph. |
| 31% | BACKTOBLOOD | 11 | Novel about Cuban immigrants by Tom Wolfe (March 2, 1930-May 14, 2018) (3 wds.) |
| 31% | FLIGHTBEHAVIOR | 14 | 2012 Barbara Kingsolver novel about a colony of butterflies in Tennessee: 2 wds. |
| 31% | SALEMSLOT | 9 | Stephen King novel about a town of vampires: 2 wds. |
| 31% | GOINGROGUE | 10 | Novel in Janet Evanovich's 32-Across series subtitled "Rise and Shine Twenty-Nine" (2 wds.) |
| 31% | WHATALICE | 9 | With 19-Across, 2009 Liane Moriarty novel about a mother who develops amnesia: 2 wds. |
| 31% | BRIGHTLIGHTS | 12 | HBO documentary about the mother-daughter relationship of 32- and 42-Across: 2 wds. |
| 30% | BIGLITTLELIES | 13 | Novel by 32-Across that was made into the 2017 HBO murder-mystery miniseries about seemingly perfect lives (3 wds.) |
| 30% | SHUTTERISLAND | 13 | 2003 18-Across novel about a mental hospital that was made into a 2010 Leonardo DiCaprio film: 2 wds. |
| 30% | KILLINGFLOOR | 12 | Debut novel by 25-Across that was the basis for the first season of "Reacher" (2 wds.) |
| 30% | WHATYOUWISHFOR | 14 | Katherine Center novel about a school librarian and her relationship with the principal (4 wds.) |
| 30% | THESTAND | 8 | Stephen King novel about a group of people who survive a worldwide pandemic: 2 wds. |
| 30% | ANXIOUSPEOPLE | 13 | 2020 best-selling novel about a group held hostage by a bank robber: 2 wds. |
| 30% | THEBEETQUEEN | 12 | 32-Across novel that features a town's root vegetable crop (3 wds.) |
| 30% | FLYINGANGELS | 12 | 2021 Danielle Steel novel about World War II nurses: 2 wds. |
| 30% | HARLEMSHUFFLE | 13 | 2021 Colson Whitehead novel about a furniture salesman drawn into a life of crime: 2 wds. |
| 29% | MRSDALLOWAY | 11 | Virginia Woolf's novel about a day in the life of a woman in England post World War I: 2 wds. |
| 29% | THELIGHTHOUSE | 13 | "To ___," writer Virginia Woolf's novel about the Ramsay family's visits to the Isle of Skye: 2 wds. |
| 29% | TARBABY | 7 | 1981 Toni Morrison novel about an educated fashion model in love with a poor fugitive: 2 wds. |
| 29% | DRAGONTATTOO | 12 | "The Girl With the ___," novel about teen hacker Lisbeth Salander, who has distinctive body art: 2 wds. |
| 29% | THEPARISWIFE | 12 | 2011 novel by 40-Across about Ernest Hemingway's first marriage (3 wds.) |
| 29% | LOVEANDRUIN | 11 | 2018 novel by 40-Across about Ernest Hemingway's third marriage (3 wds.) |
| 29% | OFMARRIED | 9 | "The World Is Full ___ Men," English novelist Jackie Collins' (birthday today) debut novel published in 1968: 2 wds. |
| 29% | THEALCHEMIST | 12 | Paulo Coelho novel about a boy who travels to find a treasure at the Egyptian pyramids: 2 wds. |
| 29% | KIPOANDTHEAGE | 13 | With 32-Across, animated series about a girl from beneath the Earth's surface: 4 wds. |
| 28% | REMEMBERME | 10 | Mary Higgins Clark novel about a grieving mother (2 wds.) |