| 100% | COPS | 4 | 32-season reality show canceled in response to 2020 protests |
| 41% | REACT | 5 | Show emotion in response to something |
| 37% | IDOL | 4 | Reality show title won by Just Sam in 2020 |
| 32% | QUEEREYE | 8 | Reality show whose cast appeared in the music video for Taylor Swift's "You Need to Calm Down" |
| 32% | HARRY | 5 | ___ Johnson and Beaux Raymond, TV personalities who won the reality show "Too Hot to Handle" in 2022 |
| 32% | WINCESAT | 8 | Flinches in response to |
| 32% | THEXFILES | 9 | First Fox show to finish in Nielsen's top 20 for a season |
| 31% | THEVOICE | 8 | American reality show hosted by Carson Daly, which works in a format similar to 21-Across: 2 wds. |
| 31% | REACTS | 6 | Acts in response to something |
| 31% | ACTSON | 6 | Takes steps in response to |
| 31% | ACTON | 5 | Do something in response to |
| 31% | PENAMERICA | 10 | Literary organization that cancelled its prize ceremony amid protests of its response to the war in Gaza (April, 2024) |
| 31% | AREYOU | 6 | Question in response to "I am" |
| 31% | PARENTSTRIKE | 12 | Walkout in response to unruly kids? |
| 31% | ILLGETIT | 8 | Words in response to a doorbell |
| 31% | ENCORE | 6 | Extra performance in response to applause |
| 31% | ANSWERS | 7 | Solutions given in response to questions |
| 31% | BOW | 3 | Bend over in response to applause |
| 31% | ARENTI | 6 | Smug question in response to praise |
| 31% | CBS | 3 | Network that plans to end the "Judge Judy" show in 2021 after its 25th season |
| 30% | AMI | 3 | Question in response to an insult, maybe |
| 30% | REFLEX | 6 | Involuntary movement in response to a stimulus |
| 30% | AMEN | 4 | Word shouted in response to a pastor |
| 30% | NCAA | 4 | Org. formed in response to football injuries |
| 30% | CANCELCULTURE | 13 | Controversial phenomenon in response to controversial actions |
| 30% | WHOWANTSTOKNOW | 14 | Sassy question in response to a question |
| 30% | USN | 3 | Org. founded in response to Barbary pirates |
| 30% | TRASHTV | 7 | Reality shows, to some people |
| 30% | OOF | 3 | Response to "pow!" in cartoons |
| 30% | AYE | 3 | Response to "All in favor" |