| 100% | ROSENYLUND | 10 | 33-Across' role on 48-/55-Across: 2 wds. |
| 64% | BOBODENKIRK | 11 | "Breaking Bad" actor who plays the lead role on 33-Across: 2 wds. |
| 56% | JAREDPADALECKI | 14 | He plays Sam Winchester on 48-Across: 2 wds. |
| 56% | JENSENACKLES | 12 | He plays Dean Winchester on 48-Across: 2 wds. |
| 56% | JOSIAHBARTLET | 13 | Presidential role on 37-Across: 2 wds. |
| 55% | UNCLEJESSE | 10 | Role played by 18-Across on "Full House": 2 wds. |
| 55% | JOHNNYGILBERT | 13 | Announcer on 48-Across since 1984: 2 wds. |
| 54% | DANIELLEFISHEL | 14 | Actress who plays Topanga Matthews on 33-Across: 2 wds. |
| 54% | SHERLOCKHOLMES | 14 | Jonny Lee Miller's role on 19-Across: 2 wds. |
| 53% | THEGOLDEN | 9 | With 55-Across, 1985-92 sitcom costarring 33-Across: 2 wds. |
| 53% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 52% | UNCLEPHIL | 9 | 48-Across's male guardian on "The Fresh Prince of Bel-Air": 2 wds. |
| 52% | AUNTVIV | 7 | 48-Across's female guardian on "The Fresh Prince of Bel-Air": 2 wds. |
| 52% | ROWANBLANCHARD | 14 | Actress who plays Topanga's daughter Riley on 33-Across: 2 wds. |
| 52% | ADAMSCOTT | 9 | "Parks and Recreation" actor who was nominated for an Emmy for his role as Mark Scout on 48-Across (2 wds.) |
| 52% | DONPARDO | 8 | Announcer on 5-Across and 48-Across who died on August 18, 2014: 2 wds. |
| 52% | LITTLEJOE | 9 | Youngest son of 33-Across on "Bonanza," played by Michael Landon: 2 wds. |
| 52% | RONKOVIC | 8 | 54-Across's role in "Born on the Fourth of July": 2 wds. |
| 51% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 51% | MOSDEF | 6 | Rapper who had a recurring role on "Dexter": 2 wds. |
| 50% | BILLYBOB | 8 | With 48-Across, "Bad Santa" star who played a serial killer on FX's "Fargo": 2 wds. |
| 50% | EDIEBRITT | 9 | Nicollette Sheridan's role on "Desperate Housewives": 2 wds. |
| 50% | DONDRAPER | 9 | Jon Hamm's role on "Mad Men": 2 wds. |
| 50% | BRADLEYCOOPER | 13 | "Silver Linings Playbook" actor who played 48-Across's love interest in 33-Across: 2 wds. |
| 50% | RHEASEEHORN | 11 | Actress who plays Jimmy McGill's love interest, lawyer Kim Wexler, on 33-Across: 2 wds. |
| 49% | ATISKETATASKET | 14 | Hit song by 48-Across based on a nursery rhyme (2 wds.) |
| 49% | CHRISTIANBALE | 13 | "American Hustle" actor who won an Oscar for his role in 48-Across' "The Fighter": 2 wds. |
| 48% | HANKAZARIA | 10 | "The Simpsons" voice actor who won an Emmy for his guest role as Ed Cochran on 43-Across: 2 wds. |
| 48% | KOREYWISE | 9 | Exonerated suspect portrayed by 33-Across in the miniseries "When They See Us" on 19-Across: 2 wds. |
| 48% | DONNIEWAHLBERG | 14 | New Kids on the Block singer who played Detective Danny Reagan on 48-Across and will reprise the role in a new series in 2025 (2 wds.) |