| 100% | JOHNFKENNEDY | 12 | 35th US president whose middle initial stands for Fitzgerald: 3 wds. |
| 71% | HARRYSTRUMAN | 12 | 33rd US president whose middle initial doesn't stand for a particular name: 3 wds. |
| 56% | GEORGEHWBUSH | 12 | 41st US president whose two middle initials stand for Herbert and Walker: 4 wds. |
| 45% | JOHNFKENNEDY | 12 | 35th US president for whom a New York City airport was renamed in 1963: 3 wds. |
| 44% | CHUCKECHEESE | 12 | Rodent mascot whose middle initial stands for "Entertainment" |
| 41% | MARSHAPJOHNSON | 14 | Key figure in the Stonewall uprising, whose middle initial stood for “Pay it no mind” |
| 39% | JOHNFKENNEDY | 12 | 35th US president, who served in the Navy during World War II: 3 wds. |
| 37% | JOHNFKENNEDY | 12 | 35th US president (1961-1963) who was on the varsity swim team at Harvard: 3 wds., abbr. |
| 37% | JOHNFKENNEDY | 12 | 35th US president who published "Profiles in Courage" in 1956, while he was a senator: 3 wds. |
| 35% | JFK | 3 | 35th US president initials |
| 34% | KENNEDY | 7 | 35th US president, whose library is located in Boston, Massachusetts |
| 32% | LSAT | 4 | Exam whose first initial stands for "Law" |
| 32% | ATM | 3 | Abbreviation whose middle letter stands for "teller" |
| 31% | WARRENGHARDING | 14 | US president who had a pet squirrel named Pete: 3 wds. |
| 31% | IOWEYOU | 7 | What "IOU" stands for: 3 wds. |
| 31% | AHS | 3 | FX show whose middle letter stands for "horror" |
| 30% | TCM | 3 | Cable channel whose first initial stands for its founder |
| 30% | MILNE | 5 | Writer whose initials stood for Alan Alexander |
| 30% | ULYSSESSGRANT | 13 | US president who signed legislation in 1872 establishing 18-Across: 3 wds. |
| 29% | MRT | 3 | TV star whose initial stands for Tureaud |
| 29% | MARTINVANBUREN | 14 | 8th US president who spoke Dutch as his first language: 3 wds. |
| 28% | GEORGEHWBUSH | 12 | 41st US president for whom a Houston airport was renamed in 1997: 4 wds. |
| 28% | KENNEDY | 7 | 35th us president |
| 28% | ULYSSESSGRANT | 13 | US president who got a speeding ticket while driving his horse and buggy in Washington: 3 wds. |
| 28% | JOHNFKENNEDY | 12 | Former US President who authored the Pulitzer Prize-winning book "Profiles in Courage": 3 wds. |
| 28% | RONALDREAGAN | 12 | 40th US president for whom a DC-area airport was renamed in 1998: 2 wds. |
| 28% | SSN | 3 | Fig. whose middle two digits were originally proposed to stand for one's birth month |
| 27% | JIMMYCARTER | 11 | 39th US president who published "Why Not the Best?" in 1976, for his presidential campaign: 2 wds. |
| 27% | TAFT | 4 | President whose middle name was Howard |
| 27% | KENNEDYCENTER | 13 | Washington, D.C., performing arts venue named for the 35th president (2 wds.) |