| 100% | SILVER | 6 | A __ bullet is the only way to kill a werewolf |
| 60% | SILVER | 6 | Type of bullet that is said to kill a werewolf |
| 54% | DESADE | 6 | He wrote "The only way to a woman's heart is along the path of torment" |
| 51% | USED | 4 | After 2004, the only way to buy a 14-Across |
| 51% | ARE | 3 | "The only way to prove you ___ a good sport is to lose" (Ernie Banks) |
| 50% | GRAPHICNOVEL | 12 | "Maus" is the only one to win a Pulitzer Prize (1992) |
| 49% | ROD | 3 | Laver who is the only player to achieve a tennis Grand Slam twice |
| 49% | WALTERBENJAMIN | 14 | German philosopher who wrote, “The only way of knowing a person is to love them without hope” |
| 48% | EAR | 3 | A mantis is the only animal known to have just one of these |
| 48% | NINA | 4 | García who is the only person to be a judge on every season of "Project Runway" |
| 48% | CURIE | 5 | Marie who is the only person to win a Nobel Prize in two different science fields |
| 45% | WILT | 4 | ___ Chamberlain, American basketball player who is the only player to score 100 points in a single NBA game |
| 42% | PIECEBYPIECE | 12 | Only way to tackle a 57-Across |
| 42% | GOLDENSLUMBERS | 14 | 1969 song with the lyric "Once there was a way to get back homeward" |
| 42% | ALI | 3 | Athlete who said, “I should be a postage stamp. That’s the only way I’ll ever get licked” |
| 41% | EARNIT | 6 | The only way to get respect, so they say |
| 41% | WIN | 3 | Be the first one to finish a race, say |
| 41% | SILVER | 6 | Metal supposedly needed to kill a werewolf |
| 41% | LILLIANGISH | 11 | "The Birth of a Nation" star who is the only silent era actor to win the AFI Life Achievement Award: 2 wds. |
| 41% | RAMBLINGROSE | 12 | 1991 drama starring 16-Across and 39-Across that is the only film to have a mother and daughter both nominated for an Oscar for the same film (2 wds.) |
| 41% | EGG | 3 | The hundred folds on a chef's toque are said to represent the number of ways to prepare this |
| 41% | ZEE | 3 | Arizona is the only state to have one |
| 41% | FAIL | 4 | "The only way to ___ is not to fight," quote by Amelia Shepherd on "Grey's Anatomy" |
| 40% | SKELETON | 8 | The Blue ridge coral is the only one that forms a __ |
| 40% | STATE | 5 | Washington is the only one named for a president |
| 40% | BUCHANAN | 8 | Only president to be a lifelong bachelor |
| 40% | RYE | 3 | Pliny the Elder wrote that this food "of a dark and sombre color" is a "poor food and only serves to avert starvation" |
| 40% | ADLER | 5 | Irene who was the only woman to outwit Sherlock Holmes |
| 40% | HARPER | 6 | First name of the author of To Kill a Mockingbird |
| 40% | TEBOW | 5 | Tim who was the first sophomore to win a Heisman |