| 100% | COLOSSALSQUID | 13 | A massive, tentacled sea creature that is one of the largest animals on the planet and is the largest known invertebrate: 2 wds. |
| 48% | ROCKIGUANA | 10 | The Jamaican ___, a lizard that is one of the rarest creatures, and was declared extinct before being found again in 1970: 2 wds. |
| 48% | RHINOCEROS | 10 | The White ___, one of the largest terrestrial animals on the planet that is known for its large horn |
| 46% | SPERMWHALE | 10 | One of the largest animals on the planet which, while smaller than its "blue" cousin, has the biggest brain proportional to its body: 2 wds. |
| 46% | BOXJELLYFISH | 12 | Umbrella-shaped invertebrate that is considered the most venomous animal on the planet: 2 wds. |
| 42% | MOUSELEMUR | 10 | A species unique to Madagascar that is the world's smallest primate and one of the smallest mammals in the world: 2 wds. |
| 41% | TORTOISE | 8 | Shelled reptile and winner of a fabled race that is one of the slowest animals in the world |
| 41% | TAJMAHAL | 8 | Mausoleum in India which is one of the 7 wonders of the world and is located in a 42-acre complex: 2 wds. |
| 40% | TIGERWOODS | 10 | Considered one of the best in golf, he was central figure in a controversy that involved infidelity and ended in his divorce: 2 wds. |
| 40% | WILDKINGDOM | 11 | Nature show on Animal Planet, a revival of a 1963-1988 show that was hosted by Marlin Perkins: 2 wds. |
| 39% | CHUCKBERRY | 10 | American songwriter who was one of the pioneers of Rock and Roll and was known for his song "Johnny B. Goode": 2 wds. |
| 39% | INTRANSLATION | 13 | "Lost ___," a romantic comedy starring Bill Murray and Scarlett Johansson, that is considered one of the best movies of the 2000s: 2 wds. |
| 39% | RYANREYNOLDS | 12 | Movie star whose first major role was one of the guys on the sitcom "Two Guys and a Girl" (2 wds.) |
| 38% | SWEETDAY | 8 | "One ___," a song by Mariah Carey and Boyz II Men, that was Billboard's most successful song of the 1990s: 2 wds. |
| 38% | SSW | 3 | One of the half winds on a compass rose that was named "Ostro-Libeccio" in the 14th and 15th centuries |
| 37% | BIBLIOTECA | 10 | ___ di Brera, a public library in Milan that is one of the largest libraries in Italy |
| 37% | ACTAFOOL | 8 | Single from Ludacris that was part of the soundtrack for "2 Fast 2 Furious," and was also nominated for a Grammy: 3 wds. |
| 37% | CANTSTOP | 8 | A song by 31-Across co-written by Frusciante, which is one of the songs that the band play live the most: 2 wds. |
| 36% | DAVIDDUCHOVNY | 13 | American actor that reportedly has an IQ of 147, and is best known for his roles on "The X-Files" and "Californication": 2 wds. |
| 36% | RAYCHARLES | 10 | "Georgia on My Mind" singer who was a charter inductee into the Rock and Roll Hall of Fame: 2 wds. |
| 36% | SUEME | 5 | Snide challenge which was also the name of a song on "Guys and Dolls": 2 wds. |
| 36% | SINGLELADIES | 12 | "___ (Put a Ring on It)," a song by Beyonce that has become one of the best-selling singles of all time: 2 wds. |
| 36% | NIGHTLIVE | 9 | "Saturday ___," American live variety show that is regarded as one of the best, and is in its 43rd season: 2 wds. |
| 36% | OLDMAN | 6 | *"The ___ and the Sea," 1952 novel by Ernest Hemingway that was adapted into a 1958 film: 2 wds. |
| 36% | ORNEVER | 7 | "It's Now ___," a song by Elvis Presley that is based on the Italian song "O Sole Mio" and Tony Martin's "There's No Tomorrow": 2 wds. |
| 36% | EYE | 3 | A giant squid has the largest one on the planet, about the size of a human head |
| 36% | ANGELSHARK | 10 | One of the rarest creatures, that looks more like a Manta Ray than a Great White, now critically endangered due to fishing: 2 wds. |
| 36% | BRENTMUSBURGER | 14 | Sports commentator who was one the members of "The NFL Today" and is known for coining the phrase "March Madness": 2 wds. |
| 36% | RUNAWAYBRIDE | 12 | Rom-com starring Julia Roberts and Richard Gere that was one of the Top 10 box office hits of 1999 (2 wds.) |
| 35% | LADYMARMALADE | 13 | A popular song that was covered by Christina Aguilera, Lil' Kim, Mya and Pink for the soundtrack of "Moulin Rouge!": 2 wds. |