| 100% | MUTATION | 8 | A permanent alteration that changes a DNA sequence |
| 53% | DELETION | 8 | Mutation that removes a DNA sequence |
| 40% | MOODRING | 8 | A finger accessory that changes colors |
| 37% | PIECEWISE | 9 | Like a mathematical function that changes at different intervals |
| 37% | FIBONACCI | 9 | A mathematical sequence that occurs in nature |
| 37% | CODE | 4 | Sequence of numbers that unlocks a gate |
| 37% | CATALYST | 8 | Thing that causes a change |
| 36% | BRANDEDANTEATER | 15 | Mammal that has a permanent mark? |
| 36% | AGE | 3 | Number that changes on a birthday |
| 36% | NEE | 3 | Word that indicates a name change |
| 36% | NEE | 3 | Word that suggests a name change |
| 36% | STET | 4 | "Ignore that change," to a proofreader |
| 36% | DAYLIST | 7 | Portmanteau for a Spotify feature that changes depending on listening time |
| 36% | RNA | 3 | A type of nucleic acid that is not DNA |
| 36% | READONLY | 8 | A protected file that cannot be changed or edited |
| 35% | ABC | 3 | Alphabet sequence that's a TV channel |
| 35% | NEE | 3 | French word that indicates a name change |
| 35% | IOC | 3 | Sports group that's a UN Permanent Observer |
| 35% | ACCIDENTAL | 10 | Sign that changes the pitch of a note |
| 35% | STEERING | 8 | Wheel inside a car that changes the direction |
| 35% | NESS | 4 | Suffix that changes an adjective to a noun |
| 35% | TEMPORARY | 9 | A position that isn't permanent |
| 35% | SWERVING | 8 | A car that suddenly changes direction |
| 35% | BABIES | 6 | Those in need of a change |
| 34% | ESE | 3 | Suffix that may change a place into a language? |
| 34% | AGE | 3 | Number that changes for each person once a year |
| 34% | DIACRITIC | 9 | Mark found above a letter that changes its sound |
| 34% | LEAF | 4 | Part of a tree that changes color in autumn |
| 34% | SCRIM | 5 | Sheer fabric that changes the exposure of a photo |
| 34% | COLDOPEN | 8 | Scene that precedes a title sequence (and a new Merriam-Webster entry of 2023) |