| 100% | PILL | 4 | A single tablet from a doctor |
| 56% | ITEM | 4 | Single thing from a set |
| 56% | PAGE | 4 | Single sheet from a book |
| 55% | UNIT | 4 | Single entity from a group, say |
| 55% | SHOTS | 5 | Injections from a doctor |
| 55% | OTOSCOPE | 8 | Earful from a doctor |
| 54% | ROUTINEPHYSICAL | 15 | Basic exam from a doctor |
| 53% | NOTE | 4 | You may get one from a doctor |
| 52% | SAYAH | 5 | Vocal request from a doctor: 2 wds. |
| 52% | SAYAH | 5 | Request from a doctor with a tongue depressor |
| 51% | AHH | 3 | "Open up and say ___" (instruction from a doctor, perhaps) |
| 50% | UNINSTALLED | 11 | Took from a tablet, say |
| 50% | SEAL | 4 | Single-named singer of "Kiss From a Rose" |
| 49% | MONOLITH | 8 | Monument carved from a single stone |
| 49% | EGG | 3 | It's produced from a single layer |
| 49% | VARIETAL | 8 | Wine from a single type of grape |
| 48% | SABOT | 5 | Shoe made from a single block of wood |
| 48% | ONE | 3 | "__, please": box office request from a single patron |
| 48% | MONOPHONY | 9 | Melody from a single singer or instrument player |
| 48% | DIRECTSNAP | 10 | Football maneuver executed from a single wing formation |
| 47% | PIETA | 5 | Michelangelo carved it from a single slab of marble |
| 47% | ASPENS | 6 | Trees that form colonies from a single root system |
| 43% | ISSEYMIYAKE | 11 | Designer whose “A Piece of Cloth” concept entails creating a full outfit from a single tube of fabric |
| 43% | HOWWILLIKNOW | 12 | 1985 Whitney Houston single whose music video features a brief appearance from Aretha Franklin |
| 42% | SOLARIS | 7 | Planet from the eponymous book that is depicted as covered by a single massive ocean |
| 40% | THRIFTSHOP | 10 | Recent single from "The Heist" with a hugely popular video: 2 wds. |
| 40% | THOUSANDYEARS | 13 | "A ___," Christina Perri's 2011 hit single written for a movie from the "The Twilight" series: 2 wds. |
| 40% | GIVEYOURHEART | 13 | "___ a Break," hit single by Demi Lovato from her third album "Unbroken": 3 wds. |
| 40% | LIGHT | 5 | "Guiding ___," Mumford & Sons track released as a lead single from their album "Delta" |
| 39% | ONE | 3 | A single |