| 100% | THEROOKIEFEDS | 13 | ABC crime series starring 32-Across that's a spin-off of the police dramedy starring 42-Across (3 wds.) |
| 46% | THEGOODDOCTOR | 13 | ABC's medical drama TV series starring Freddie Highmore, based on a South Korean series of the same name: 3 wds. |
| 41% | LIFEONMARS | 10 | 2008-2009 ABC sci-fi crime drama series that was a remake of a British TV series: 3 wds. |
| 40% | BIGBANGTHEORY | 13 | The CBS comedy series "Young Sheldon" was created as a spin-off prequel of the hit sitcom "The ___": 3 wds. |
| 37% | STARTREK | 8 | "___: Deep Space Nine," American TV series that is a spin-off of the original |
| 37% | THEGOLDEN | 9 | "___ Palace," sitcom that was a spin-off of "The Golden Girls," in which Don Cheadle (birthday today) starred as Roland Wilson: 2 wds. |
| 37% | FBIMOSTWANTED | 13 | 2020 crime drama spun off from a Missy Peregrym series: 3 wds. |
| 37% | AHARDDAYS | 9 | "___ Night," a musical comedy film starring the Beatles that won 31-Across an Academy Award for scoring of music: 3 wds. |
| 37% | BETTERCALLSAUL | 14 | AMC show starring Bob Odenkirk, spun off from a crime drama: 3 wds. |
| 37% | ANGEL | 5 | American TV series that is a spin-off of "Buffy the Vampire Slayer" |
| 37% | FEAR | 4 | "___ the Walking Dead," American post-apocalyptic TV series that is a spin-off of "The Walking Dead" |
| 37% | THEORIGINALS | 12 | The CW Television Network's series which was created as a spin-off of the hit supernatural drama "The Vampire Diaries": 2 wds. |
| 37% | NCISNEWORLEANS | 14 | 2014 spin-off of a long-running Mark Harmon series: 3 wds. |
| 36% | THELASTSTRAW | 12 | 2009 book that was #3 in the "Diary of a Wimpy Kid" series: 3 wds. |
| 36% | THEUGLYTRUTH | 12 | 2010 book that was #5 in the "Diary of a Wimpy Kid" series: 3 wds. |
| 36% | THETHIRDWHEEL | 13 | 2012 book that was #7 in the "Diary of a Wimpy Kid" series: 3 wds. |
| 36% | GOMERPYLEUSMC | 13 | Sitcom set at a military base that was a spin-off of "The Andy Griffith Show" (3 wds.) |
| 36% | THEDIRTYDOZEN | 13 | 1967 movie that starred Lee Marvin as the head of a renegade commando group: 3 wds. |
| 36% | THEWESTWING | 11 | A political drama that debuted in the 90s, starring the likes of Rob Lowe and Martin Sheen: 3 wds. |
| 36% | THETRUMANSHOW | 13 | 1998 Peter Weir film starring Jim Carrey as the unwitting star of a reality series: 3 wds. |
| 36% | GIRL | 4 | "Gossip ___," 2021 series that's a sequel of the original series that starred Blake Lively |
| 36% | THEJEFFERSONS | 13 | Sitcom set in New York city that was a spin-off of "All in the Family" (2 wds.) |
| 35% | YEARS | 5 | "The Wonder ___," 2021 TV series that's a reboot of the original series which starred Fred Savage |
| 35% | THEKILLING | 10 | AMC/Netflix drama starring Mireille Enos that's a remake of a Danish series: 2 wds. |
| 35% | WILLTRENT | 9 | Police procedural TV series starring 16-Across, 32-Across, and a Chihuahua (2 wds.) |
| 35% | THEKARATEKID | 12 | 1984 film starring 14-Across and 31-Across that introduced the main characters of the Netflix series "Cobra Kai" (3 wds.) |
| 35% | GREYSANATOMY | 12 | ABC's medical drama TV series starring Ellen Pompeo that is set in the fictional Seattle Grace Hospital: 2 wds. |
| 35% | MELROSEPLACE | 12 | American primetime soap opera which was a spin-off of the hit teen drama series "Beverly Hills, 90210": 2 wds. |
| 35% | BETTER | 6 | "___ Call Saul," American crime drama TV series that is a spin-off, prequel, and sequel of "Breaking Bad" |
| 35% | ICARLY | 6 | 2021 TV series that's a revival of the original series starring Miranda Cosgrove |