| 100% | WALTER | 6 | Actor Matthau who frequently co-starred with Jack Lemmon |
| 50% | SONDRA | 6 | Locke who frequently co-starred with Clint Eastwood |
| 43% | WALLACH | 7 | Character actor Eli who often co-starred with his wife Anne Jackson |
| 43% | OAKIE | 5 | Jack who co-starred with Charlie Chaplin in "The Great Dictator" |
| 43% | ROBERTREDFORD | 13 | Actor who co-starred with Barbra Streisand in 31-Across (2 wds.) |
| 42% | GRANT | 5 | Actor Hugh who co-stars with Julia Roberts in "Notting Hill" |
| 42% | OHARA | 5 | Catherine who has frequently co-starred with Eugene Levy |
| 42% | HOFFMAN | 7 | Actor Dustin who co-starred with 18-Across in "Kramer vs. Kramer" |
| 41% | IAN | 3 | Actor McKellen who co-starred with Derek Jacobi on the British sitcom "Vicious" |
| 40% | OMAR | 4 | Actor Epps who co starred on House |
| 40% | RALPHFIENNES | 12 | Actor who co-stars with 38-Across and Bill Murray in "The Grand Budapest Hotel" (2 wds.) |
| 40% | ILER | 4 | Actor Robert who hosts the podcast "Not Today, Pal" with former co-star Jamie-Lynn Sigler |
| 40% | RYAN | 4 | Actor O'Neal who co-stars with 42-Across in the 1976 comedy film "Nickelodeon" |
| 39% | BENAFFLECK | 10 | Actor who co-starred with Anna Kendrick (birthday today) in the 2016 crime thriller "The Accountant": 2 wds. |
| 39% | NANCE | 5 | Actor Jack who often collaborated with David Lynch |
| 39% | DAVIDHARBOUR | 12 | "Stranger Things" actor who co-starred with Denzel Washington in "The Equalizer" (2 wds.) |
| 39% | TRACYMORGAN | 11 | "30 Rock" actor who co-stars with 29-Across in 39-Across (2 wds.) |
| 39% | TOMMYLEEJONES | 13 | Oscar-winning actor who co-stars with Matt Damon in "Jason Bourne" (3 wds.) |
| 38% | BASS | 4 | Alfie ---, comedy actor who co-starred with Bill Fraser in ITV sitcom Bootsie and Snudge |
| 38% | CHRISTIANBALE | 13 | Oscar-winning actor who co-stars with Matt Damon in "Ford v Ferrari" (2 wds.) |
| 38% | GEORGECLOONEY | 13 | Actor who co-stars with 38-Across in "Michael Clayton" and with Bill Murray in "The Monuments Men" (2 wds.) |
| 38% | OMAR | 4 | Actor Sharif who starred with Barbra Streisand in "Funny Girl" |
| 38% | PETER | 5 | With 7-Across, late actor who starred in "Easy Rider" |
| 38% | BASS | 4 | Alfie —, comedy actor who co-starred with Bill Fraser in 1960s ITV sitcom Bootsie and Snudge |
| 38% | ANDREWLINCOLN | 13 | "The Walking Dead" actor who co-starred with Bill Nighy in "Love, Actually" (2 wds.) |
| 37% | DENZEL | 6 | With 26-Across, "Malcolm X" actor who stars in 40-Across |
| 37% | MORGANFREEMAN | 13 | "Going in Style" actor who co-starred with Tom Cruise in 2013's "Oblivion" (2 wds.) |
| 37% | JOSEPH | 6 | With 14- and 45-Across, "Inception" actor who stars in 49-Across |
| 37% | WILLARD | 7 | Late comic actor Fred who frequently collaborated with Christopher Guest |
| 36% | JOHN | 4 | With 39-Across, "Snowpiercer" actor who starred as John Merrick in 16-Across |