| 100% | JONATHANGROFF | 13 | Actor who originated the role of 15-Across on Broadway (2 wds.) |
| 70% | RAMOS | 5 | Actor who originated the role of Hamilton on Broadway |
| 62% | RICHARDGERE | 11 | Actor who accepted the role of Edward in 17-Across: 2 wds. |
| 61% | CAROLBURNETT | 12 | "Better Call Saul" actress who originated the role of Princess Winnifred in the 1959 Broadway production of "Once Upon a Mattress": 2 wds. |
| 61% | REEVE | 5 | Actor/singer ___ Carney, who originated the role of Orpheus in "Hadestown" on Broadway |
| 57% | MARYMARTIN | 10 | Actress who originated the roles of Peter Pan and Maria von Trapp on Broadway |
| 55% | TOPHERGRACE | 11 | Actor who played the role of Eric Forman in the TV show "That '70s Show": 2 wds. |
| 54% | LEVENE | 6 | Classic Broadway actor Sam who originated the role of Nathan Detroit |
| 54% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 54% | ZACEFRON | 8 | Actor who plays a protégé of 15-Across in "The Greatest Showman": 2 wds. |
| 54% | BOBODENKIRK | 11 | "Breaking Bad" actor who plays the lead role on 33-Across: 2 wds. |
| 53% | LIEVSCHREIBER | 13 | "Spotlight" actor who has been nominated for three Emmys for playing the title role on 43-Across: 2 wds. |
| 53% | DONNYOSMOND | 11 | Actor who was the Peacock on season 1 of "The Masked Singer": 2 wds. |
| 52% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 52% | PAULSCHNEIDER | 13 | Actor who played the role of Mark Brendanawicz in "Parks and Recreation", a character that appeared only in the first two seasons: 2 wds. |
| 52% | MANDYPATINKIN | 13 | Tony- and Emmy-winning actor who was a guest on the "On Broadway" episode of "Finding Your Roots" in 2021 (2 wds.) |
| 52% | WENDELLPIERCE | 13 | "The Wire" actor who starred in "Death of a Salesman" on Broadway in 2022: 2 wds. |
| 51% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 51% | FESSPARKER | 10 | Actor who starred in the title roles of TV's "Davy Crockett" and "Daniel Boone": 2 wds. |
| 51% | IKEBARINHOLTZ | 13 | "The Afterparty" actor who plays executive Sal Saperstein on 15-Across: 2 wds. |
| 51% | JONBARINHOLTZ | 13 | "Superstore" actor who plays Wesley Payne, grandson of the former CEO, on "American Auto": 2 wds. |
| 51% | DENNISQUAID | 11 | "Flight of the Phoenix" actor who plays the title role in 16-Across: 2 wds. |
| 51% | SOO | 3 | Actress Phillipa who originated the role of Eliza in Broadway's "Hamilton" |
| 51% | IDINA | 5 | Actress Menzel who originated the role of Elphaba in Broadway's "Wicked" |
| 51% | MORGANFREEMAN | 13 | Actor who portrayed 15-Across in the 2009 film "Invictus": 2 wds. |
| 51% | SEANGIAMBRONE | 13 | Actor who plays the geeky boy, Adam, on 18-Across: 2 wds. |
| 51% | ALEXNEWELL | 10 | Actor who won a Tony in 2023 for their role as Lulu in the Broadway musical "Shucked": 2 wds. |
| 50% | LEN | 3 | He originated the role of Sweeney on Broadway |
| 50% | WILLSMITH | 9 | "Men in Black" actor who played the role of Oscar in the animated film "Shark Tale": 2 wds |
| 50% | NIMOY | 5 | Actor Leonard who originated the role of Spock |