| 100% | ROBINWILLIAMS | 13 | Actor who played Daniel Hillard, and the title character, in the 1993 film "Mrs. Doubtfire": 2 wds. |
| 76% | ROBINWILLIAMS | 13 | "Good Will Hunting" actor who played Daniel Hillard and the title housekeeper in "Mrs. Doubtfire" (2 wds.) |
| 62% | ROBINWILLIAMS | 13 | "Good Will Hunting" actor who played the nanny Mrs. Doubtfire in the 1993 film: 2 wds. |
| 58% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 57% | SALLYFIELD | 10 | "80 for Brady" actress who played Miranda Hillard in the 1993 film "Mrs. Doubtfire" (2 wds.) |
| 56% | KENNETHBRANAGH | 14 | Actor who directed and played the title character in 1996's "Hamlet": 2 wds. |
| 56% | PETERSELLERS | 12 | Actor who played Pres. Merkin Muffley, Group Capt. Lionel Mandrake, and the title character in 32-Across: 2 wds. |
| 54% | MELGIBSON | 9 | Actor who played the lead character, "Mad" Max Rockatansky in the 1979 film "Mad Max": 2 wds. |
| 54% | ROBINWILLIAMS | 13 | "Mrs. Doubtfire" actor who played Peter Pan in the 1991 film "Hook": 2 wds. |
| 53% | DANIELKALUUYA | 13 | Actor who plays Slim, one of the title characters on the run in 2019's "Queen & Slim": 2 wds. |
| 53% | EDWARDNORTON | 12 | "Fight Club" actor who plays Lionel Essrog in "Motherless Brooklyn" and also directed the film: 2 wds. |
| 52% | EZRAMILLER | 10 | Actor who plays the title character in the new movie "The Flash": 2 wds. |
| 52% | TOMHARDY | 8 | "Inception" actor who plays the title character in "Venom": 2 wds. |
| 52% | ORSONWELLES | 11 | Actor who directed 17-Across and played the title character: 2 wds. |
| 51% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 51% | NAVIDNEGAHBAN | 13 | Actor who appeared in "24," "Homeland" and is playing The Sultan in 2019 film "Aladdin": 2 wds. |
| 51% | ANSELELGORT | 11 | "The Fault in Our Stars" actor who plays the title character in "Baby Driver": 2 wds. |
| 51% | TARONEGERTON | 12 | "Kingsman: The Golden Circle" actor who plays the title character in 16-Across: 2 wds. |
| 51% | FERDIASHAW | 10 | Young actor who plays the title character in the 2020 movie "Artemis Fowl": 2 wds. |
| 51% | PETERDINKLAGE | 13 | "Game of Thrones" actor who plays the title character in "The Toxic Avenger": 2 wds. |
| 51% | VINDIESEL | 9 | Actor who plays Dominic Toretto in the "Fast and Furious" films (2 wds.) |
| 51% | JASONSTATHAM | 12 | "The Expendables" actor who plays Lee Christmas in the 2010 film and also starred as Chev Chelios in "Crank": 2 wds. |
| 50% | JONFAVREAU | 10 | Actor who plays Happy Hogan in Marvel films, and has directed the pilot for "The Orville": 2 wds. |
| 50% | MICHAELCIMINO | 13 | "Annabelle Comes Home" actor who plays the newly out title character in "Love, Victor": 2 wds. |
| 50% | TIMOTHYHUTTON | 13 | "Ordinary People" actor who plays two roles in the 1993 film adaptation of 44-Across (2 wds.) |
| 50% | DOLPHLUNDGREN | 13 | "The Expendables" actor who plays Gunner Jensen in the 2010 film and also starred as He-Man in "Masters of the Universe": 2 wds. |
| 49% | HARRISONFORD | 12 | "The Fugitive" actor who plays the title role in "Indiana Jones and the Dial of Destiny" (2 wds.) |
| 49% | JAKELLOYD | 9 | Actor who played Anakin Skywalker in the film mentioned in 16a: 2 wds. |
| 49% | TOMMYLEEJONES | 13 | Actor who plays Agent K in the "Men in Black" films and who played football at Harvard (2 wds.) |
| 49% | OSCARISAAC | 10 | Actor who plays Gomez Addams in the 2019 film "The Addams Family" and in its 2021 sequel (2 wds.) |