| 100% | FREDSAVAGE | 10 | Actor who played Kevin Arnold on the original 32-Across and who directed the first episode of the 2021 reboot of 32-Across (2 wds.) |
| 64% | FREDSAVAGE | 10 | Actor who played Kevin Arnold in the original version of 36-Across and is coproducing the reboot: 2 wds. |
| 45% | JUSTINHARTLEY | 13 | "The Young and the Restless" actor who plays Kevin Pearson on "This Is Us": 2 wds. |
| 44% | KENNETHCHOI | 11 | Actor who played Chester Ming on "The Wolf of Wall Street" and portrays the role of Judge Lance Ito in "American Crime Story" : 2 wds. |
| 44% | MANDYPATINKIN | 13 | Tony- and Emmy-winning actor who was a guest on the "On Broadway" episode of "Finding Your Roots" in 2021 (2 wds.) |
| 44% | BRUCEMCGILL | 11 | "The Best of Enemies" actor who played Jack Dalton on the original "MacGyver" (2 wds.) |
| 42% | JOSHOCONNOR | 11 | "Emma" actor who played 32-Across in seasons 3 and 4 of "The Crown": 2 wds. |
| 42% | PAULSCHNEIDER | 13 | Actor who played the role of Mark Brendanawicz in "Parks and Recreation", a character that appeared only in the first two seasons: 2 wds. |
| 42% | DONCHEADLE | 10 | Emmy-nominated actor who narrates the 2021 reboot of 32-Across (2 wds.) |
| 41% | HARRISONFORD | 12 | "Indiana Jones and the Dial of Destiny" actor who plays Jimmy's mentor Paul on "Shrinking": 2 wds. |
| 41% | MIAWASIKOWSKA | 13 | Actress who played the daughter of 14- and 32-Across in "The Kids Are All Right": 2 wds. |
| 41% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 41% | STANLEYTUCCI | 12 | 19-Across and 32-Across actor who plays Dr. Abraham Erskine in "Captain America: The First Avenger" (2 wds.) |
| 40% | KENNETHBRANAGH | 14 | "Death on the Nile" actor/director who directed the first of Marvel's "Thor" films (2 wds.) |
| 40% | FREDRICMARCH | 12 | Actor who played the lawyer based on William Jennings Bryan in 32-Across: 2 wds. |
| 40% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 40% | JAYHERNANDEZ | 12 | "Scandal" actor who played Magnum on the reboot of "Magnum, P.I." (2 wds.) |
| 40% | ORSONWELLES | 11 | Actor who directed 17-Across and played the title character: 2 wds. |
| 40% | MARLONBRANDO | 12 | "The Godfather" actor who played 41-Across in the original 1940s stage production of "A Streetcar Named Desire": 2 wds. |
| 40% | PETERSELLERS | 12 | Actor who played Pres. Merkin Muffley, Group Capt. Lionel Mandrake, and the title character in 32-Across: 2 wds. |
| 40% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 40% | STEVECARELL | 11 | "The Office" actor who plays the first Chief of Space Operations on "Space Force" (2 wds.) |
| 40% | JAYHERNANDEZ | 12 | "Scandal" actor who plays Magnum on the 2018 reboot of "Magnum, P.I." (2 wds.) |
| 40% | KENNETHBRANAGH | 14 | "Murder on the Orient Express" and 45-Across star who is the only actor to direct himself playing Hercule Poirot (2 wds.) |
| 40% | DANIELKALUUYA | 13 | Actor who plays W'Kabi in the Marvel Cinematic Universe and has been on "Black Mirror": 2 wds. |
| 40% | COLINFARRELL | 12 | "Horrible Bosses" actor who plays Ray Velcoro on the latest season of "True Detective": 2 wds. |
| 39% | DULE | 4 | Actor Hill who plays the dad on the 2021 reboot of "The Wonder Years" |
| 39% | DJIMONHOUNSOU | 13 | Actor who played the wizard Shazam in DC's "Shazam!" and Korath in Marvel's "Guardians of the Galaxy": 2 wds. |
| 39% | DAMIANMCGINTY | 13 | Irish singer who played Rory Flanagan on "Glee" and was a member of 32-Across: 2 wds. |
| 39% | ANTHONYRAPP | 11 | "Star Trek: Discovery" actor who played Mark Cohen in the original Broadway cast of "Rent": 2 wds. |