| 100% | DAFOE | 5 | Actor Willem who plays a suspect on the 34-Across |
| 77% | DENCH | 5 | Actress Judi who plays a suspect on the 34-Across |
| 77% | CRUZ | 4 | Actress Penelope who plays a suspect on the 34-Across |
| 67% | DEPP | 4 | Actor Johnny who plays a murder victim on the 34-Across |
| 55% | SETH | 4 | Actor Green who played a werewolf on "Buffy the Vampire Slayer" |
| 52% | DALY | 4 | Actor Tim who plays a football team owner on the revival of "The Game" |
| 52% | ALDA | 4 | Actor Alan who played a senator on "The West Wing" |
| 50% | ILER | 4 | Actor Robert who played A.J. Soprano on "The Sopranos" |
| 50% | LOWE | 4 | Actor Rob who played a presidential aide on "The West Wing" |
| 49% | CHAR | 4 | Actor who played a character with the same first name on "Two and a Half Men" |
| 49% | STING | 5 | Rocker who plays himself, as a murder suspect, on "Only Murders in the Building" |
| 49% | JAMESBROLIN | 11 | Actor who played a physician on 28-Across: 2 wds. |
| 49% | ALDA | 4 | Actor who played a senator on “The West Wing” and in “The Aviator” |
| 49% | TED | 3 | Actor Knight who played a news anchor on "The Mary Tyler Moore Show" |
| 49% | JEFFDANIELS | 11 | Actor who won a 2013 Emmy for playing Will McAvoy, the anchor and managing editor on 37-Across: 2 wds. |
| 48% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 47% | DAVIDCASSIDY | 12 | Actor who played a singing sibling on "The Partridge Family" (2 wds.) |
| 47% | DAN | 3 | Actor Stevens who plays a mutant on FX's "Legion" |
| 47% | DANNYBONADUCE | 13 | Actor who played a guitar-playing sibling on "The Partridge Family" (2 wds.) |
| 46% | BRAD | 4 | With 34-Across, "Moneyball" actor who plays a rescuer of the novelist in "The Lost City" |
| 46% | BEN | 3 | Actor Gazzara who played the title role of 15-Across in a 1975 film |
| 46% | ROD | 3 | Actor Steiger who played the title role of 15-Across in a 1959 biopic |
| 46% | SHALHOUB | 8 | Actor Tony who plays the father of 48-Across on an Emmy-winning Amazon series |
| 46% | JAMESGARNER | 11 | Actor who played a private detective in Los Angeles on "The Rockford Files" (2 wds.) |
| 45% | MRT | 3 | Actor who played B.A. on "The A-Team": 2 wds. |
| 45% | EWANMCGREGOR | 12 | Actor who plays the protagonist in "Christopher Robin" which is a fantasy film based on "Winnie-the-Pooh": 2 wds. |
| 45% | SETH | 4 | Actor Green who played a werewolf in "Buffy the Vampire Slayer" |
| 45% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 45% | SEANGIAMBRONE | 13 | Actor who plays the geeky boy, Adam, on 18-Across: 2 wds. |
| 45% | HUDSONYANG | 10 | Actor who plays 36-Across on "Fresh off the Boat" (2 wds.) |