| 100% | ANDERSON | 8 | Actress Gillian, who played a lead role in "The X-Files" |
| 79% | DUCHOVNY | 8 | Actor David, who played a lead role in "The X-Files" |
| 63% | WINONARYDER | 11 | "Edward Scissorhands" actress, who plays a lead role in "Stranger Things": 2 wds. |
| 57% | ELLIEKEMPER | 11 | Actress who plays the lead role in 12-/24-Across: 2 wds. |
| 56% | MIRA | 4 | Actress Sorvino who has a recurring role in the web series "StartUp" |
| 55% | LEO | 3 | Actress Melissa who plays a Reverend Mother in the Vatican II drama "Novitiate" |
| 55% | OLGA | 4 | Actress Kurylenko who played a Bond girl in the 2008 film "Quantum of Solace" |
| 54% | ELISABETHMOSS | 13 | American actress who plays the lead role of Offred in the series in 18a: 2 wds. |
| 53% | AMYPOEHLER | 10 | Actress who played the role of Leslie Knope in "Parks and Recreation", a role she is best-known for: 2 wds. |
| 53% | EDIE | 4 | Actress Falco who plays a general in "Avatar: The Way of Water" |
| 53% | SARAHPAULSON | 12 | "American Horror Story" actress who won the 2024 Best Leading Actress in a Play Tony for "Appropriate": 2 wds. |
| 52% | STAR | 4 | Play a lead role in a movie |
| 51% | SIMMONS | 7 | Actress Lili who plays a "Jennifer Lawrence-type" celebrity in the new season of "Ray Donovan" |
| 51% | DAWN | 4 | Actress French who played the title role in "The Vicar of Dibley" |
| 51% | MOL | 3 | Actress Gretchen who has a recurring role on "Mozart in the Jungle" |
| 51% | DIANEKEATON | 11 | Actress who plays a mother in "Father of the Bride" (2 wds.) |
| 51% | VIOLA | 5 | Actress Davis who plays the title role in "Ma Rainey's Black Bottom" |
| 51% | DERN | 4 | Actress Laura who played a vice admiral in "The Last Jedi" |
| 51% | GRABOL | 6 | Danish Sofie who played lead role in The Killing |
| 50% | RITA | 4 | Actress Hayworth whose poster plays a big role in the movie "The Shawshank Redemption" |
| 50% | REEVES | 6 | Steve who played the title role of Hercules in a 1959 film |
| 50% | DARYLHANNAH | 11 | Actress who played the title role in 1987 romcom Roxanne |
| 50% | DENISERICHARDS | 14 | Actress who played a Bond Girl in "The World Is Not Enough" and appeared in a guest role in "Two and a Half Men": 2 wds. |
| 50% | USHER | 5 | One with a leading role in the theater? |
| 50% | CATHERINEOHARA | 14 | Former SCTV regular who won the 2020 Emmy Award for Outstanding Lead Actress in a Comedy Series for playing Moira Rose on 46-Across (2 wds.) |
| 50% | KATHYBATES | 10 | Actress who plays a marijuana dispensary owner in the new Netflix comedy "Disjointed": 2 wds. |
| 50% | UMA | 3 | Actress Thurman who played a history professor in "The Life Before Her Eyes" |
| 49% | VOSK | 4 | Jessica who played the lead role, Elphaba, in "Wicked" on Broadway in 2018-19 |