| 100% | GRACEKELLY | 10 | Actress who played a socialite in Hitchcock's "Dial M for Murder": 2 wds. |
| 53% | HELENMIRREN | 11 | "The Queen" actress who plays a retired intelligence agent in "The Thursday Murder Club": 2 wds. |
| 52% | ANNEBANCROFT | 12 | Actress who won a Tony and an Oscar for playing Helen Keller's teacher in "The Miracle Worker": 2 wds. |
| 52% | DEBRAMESSING | 12 | Actress who played 17a in the series for which she won a Primetime Emmy Award: 2 wds. |
| 50% | KRISTENSTEWART | 14 | Actress who played a vampire in 2012's "The Twilight Saga: Breaking Dawn — Part 2": 2 wds. |
| 50% | VIOLADAVIS | 10 | Actress who won a Tony and an Oscar for playing Rose Maxson in "Fences": 2 wds. |
| 50% | AMYPOEHLER | 10 | Actress who played the role of Leslie Knope in "Parks and Recreation", a role she is best-known for: 2 wds. |
| 50% | INGRIDBERGMAN | 13 | "Casablanca" actress who played a Swedish missionary in "Murder on the Orient Express": 2 wds. |
| 50% | NATALIEPORTMAN | 14 | "Black Swan" actress who plays Elizabeth Berry, an actress studying Gracie for a movie role in "May December": 2 wds. |
| 50% | CRISTINMILIOTI | 14 | Actress who plays a wedding guest who's stuck in a time loop in 44-Across: 2 wds. |
| 50% | CAMERONDIAZ | 11 | "The Mask" actress who played a private investigator named Natalie in "Charlie's Angels": 2 wds. |
| 49% | DREWBARRYMORE | 13 | "50 First Dates" actress who played a private investigator named Dylan in "Charlie's Angels": 2 wds. |
| 49% | HILARYSWANK | 11 | "Million Dollar Baby" actress who plays a journalist whose son was murdered in 31-Across (2 wds.) |
| 49% | MARGOTROBBIE | 12 | Actress who plays a fictional associate producer in "Bombshell": 2 wds. |
| 49% | MERYLSTREEP | 11 | "The Devil Wears Prada" actress who plays a struggling actress on "Only Murders in the Building" (2 wds.) |
| 49% | AUBREYPLAZA | 11 | Actress who plays a profane 14th-century nun in "The Little Hours": 2 wds. |
| 48% | FARRAHFAWCETT | 13 | "Charlie's Angels" actress who played a photographer nicknamed Beauty in "The Cannonball Run": 2 wds. |
| 48% | PIPERLAURIE | 11 | "Carrie" actress who played 27-Across's mother in "Children of a Lesser God": 2 wds. |
| 48% | SANDRABULLOCK | 13 | "The Blind Side" actress who played a crossword constructor in 33-Across: 2 wds. |
| 48% | KATEYSAGAL | 10 | "Sons of Anarchy" actress who plays a police officer in "Superior Donuts": 2 wds. |
| 48% | DIANNEWIEST | 11 | "Bullets Over Broadway" actress who plays a grandma on "Life in Pieces": 2 wds. |
| 48% | KATHYBATES | 10 | Actress who plays a marijuana dispensary owner in the new Netflix comedy "Disjointed": 2 wds. |
| 48% | LOUISEFLETCHER | 14 | Actress who won a Best Actress Oscar for playing 46-Across in the 1975 film "One Flew Over the Cuckoo's Nest" (2 wds.) |
| 47% | VIOLADAVIS | 10 | "Fences" actress who plays a government official in "The Suicide Squad": 2 wds. |
| 47% | BRIELARSON | 10 | Actress who plays the character of Carol Danvers, a former U.S. Air Force pilot in "Captain Marvel": 2 wds. |
| 47% | OLIVIACOOKE | 11 | "Ready Player One" actress who plays the pregnant girlfriend of a murdered man in 31-Across (2 wds.) |
| 47% | SANDRABULLOCK | 13 | "Ocean's 8" actress who plays a novelist kidnapped in the jungle in "The Lost City": 2 wds. |
| 47% | WHOOPIGOLDBERG | 14 | Actress who won a Best Supporting Actress Oscar for playing 19-Across in 62-Across (2 wds.) |
| 47% | ELIZABETHOLSEN | 14 | Actress who plays a powerful witch in Marvel's "Avengers" films and on 44-Across (2 wds.) |
| 46% | BENKINGSLEY | 11 | "Gandhi" actor who plays a retired psychiatrist in "The Thursday Murder Club": 2 wds. |