| 100% | VICKILAWRENCE | 13 | Actress who played Mama Thelma Harper in "The Family" skits with 38-Across (2 wds.) |
| 53% | ISABELSANFORD | 13 | Actress who played Louise on "All in the Family" and 45-Across (2 wds.) |
| 52% | EVELYNKEYES | 11 | Actress who played Suellen O'Hara in the film "Gone With the Wind": 2 wds. |
| 52% | JEANSTAPLETON | 13 | Actress who played mom Edith Bunker on "All in the Family": 2 wds. |
| 52% | JEANSTAPLETON | 13 | "All in the Family" actress who played Edith Bunker: 2 wds. |
| 51% | ISABELSANFORD | 13 | "All in the Family" actress who played the Bunkers' neighbor Louise Jefferson: 2 wds. |
| 50% | HARVEYKORMAN | 12 | Actor who played Mother Marcus in "As the Stomach Turns" skits with 38-Across (2 wds.) |
| 49% | ELLIEKEMPER | 11 | Actress who plays the lead role in 12-/24-Across: 2 wds. |
| 49% | ANGELABASSETT | 13 | Actress who played rock star Tina Turner in the 1993 film "What's Love Got to Do With It": 2 wds. |
| 49% | NEVECAMPBELL | 12 | "Scream" actress who played Bonnie Harper in "The Craft": 2 wds. |
| 48% | JULIECHRISTIE | 13 | "Shampoo" actress who played Lara in the 1965 film version of 19-Across: 2 wds. |
| 48% | LIVTYLER | 8 | "Armageddon" actress who played the lead singer's girlfriend Faye in 34-Across: 2 wds. |
| 47% | VIVIENLEIGH | 11 | Actress who played Scarlett O'Hara in the film "Gone With the Wind" and also won an Oscar for her work in the film: 2 wds. |
| 47% | NATASHALYONNE | 13 | "Poker Face" actress who plays Mama Poot in "Smurfs": 2 wds. |
| 47% | MIAWASIKOWSKA | 13 | Actress who played the daughter of 14- and 32-Across in "The Kids Are All Right": 2 wds. |
| 47% | RACHELMCADAMS | 13 | "Doctor Strange" actress who plays the title character's mom in 33-/49-Across: 2 wds. |
| 47% | KRYSTENRITTER | 13 | "Jessica Jones" actress who plays Lucy in the "Echoes" spin-off of 18-Across: 2 wds. |
| 47% | ANGELABASSETT | 13 | Actress who plays Tina Turner in the music biopic "What's Love Got to Do with It" (2 wds.) |
| 46% | PENELOPEANN | 11 | With 50-Across, "Carlito's Way" actress who plays the First Lady in 16-Across: 2 wds. |
| 46% | BLAKELIVELY | 11 | "Gossip Girl" actress who plays Lily Bloom in the 2024 film "It Ends With Us" (2 wds.) |
| 46% | MARGARETAVERY | 13 | Actress who plays Shug in "The Color Purple" who reunites with co-star Danny Glover in 28-Across (2 wds.) |
| 46% | BLAKELIVELY | 11 | Actress who plays the "It Girl" in "Gossip Girl": 2 wds. |
| 46% | CARROLL | 7 | With 38-Across, "All in the Family" actor who played Archie Bunker |
| 46% | ANNEARCHER | 10 | Actress who played Beth Gallagher, the wife, in "Fatal Attraction": 2 wds. |
| 46% | KATHYBATES | 10 | Actress who played Margaret "Molly" Brown in the movie "Titanic": 2 wds. |
| 46% | HAYLEYATWELL | 12 | Actress who plays Grace in the new "Mission: Impossible" movie: 2 wds. |
| 46% | EMMATHOMPSON | 12 | Oscar-winning actress who plays P.L. Travers, author of the novel "Mary Poppins," in 32-Across: 2 wds. |
| 46% | KEELEYHAWES | 11 | "The Missing" actress who plays Dr. Kira Manning in the "Echoes" spin-off of 18-Across: 2 wds. |
| 46% | BROOKESHIELDS | 13 | Actress who played Sheila Porter in the latest season of "Law & Order: SVU": 2 wds. |
| 46% | KATHYBATES | 10 | Actress who plays a marijuana dispensary owner in the new Netflix comedy "Disjointed": 2 wds. |