| 100% | LINDALAVIN | 10 | Actress who played the title character on the sitcom "Alice": 2 wds. |
| 79% | EDIEFALCO | 9 | "The Sopranos" actress who played the title character on "Nurse Jackie": 2 wds. |
| 76% | LILYCOLLINS | 11 | Actress who plays the title character on 46-Across (2 wds.) |
| 75% | BROOKESHIELDS | 13 | "The Blue Lagoon" actress who played the title character on 46-Across (2 wds.) |
| 75% | LOUISAHARLAND | 13 | "Derry Girls" actress who plays the title character on 44-Across (2 wds.) |
| 73% | CAMILLERAZAT | 12 | Actress who plays the title character's new friend on 46-Across (2 wds.) |
| 72% | EMMANUELLEWIS | 13 | Actor who played the title character on "Webster": 2 wds. |
| 72% | BARBARABARRIE | 13 | "Breaking Away" actress who played the title character's Nana on 46-Across (2 wds.) |
| 72% | MARGOTROBBIE | 12 | "Babylon" actress who plays the title character in "Barbie": 2 wds. |
| 71% | SARAHPAULSON | 12 | "American Horror Story" actress who plays the title character, 46-Across, on a Netflix miniseries (2 wds.) |
| 71% | TOMHIDDLESTON | 13 | "Kong: Skull Island" star who plays the title character on "Loki": 2 wds. |
| 71% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 71% | KENNEDYMCMANN | 13 | Actress who plays the title role on "Nancy Drew": 2 wds. |
| 70% | SUSANSARANDON | 13 | Actress who played Louise, one of the title characters on the run in 1991's "Thelma & Louise": 2 wds. |
| 70% | SARAHPAULSON | 12 | "American Horror Story" actress who plays the title character in Netflix's "Ratched": 2 wds. |
| 70% | SUSANCLARK | 10 | Actress who played the adoptive mother on the 1980s sitcom "Webster": 2 wds. |
| 69% | POLLYHOLLIDAY | 13 | Actress who played waitress Flo on the sitcom "Alice": 2 wds. |
| 68% | PEDROPASCAL | 11 | "Narcos" actor who plays the title character on "The Mandalorian" (2 wds.) |
| 67% | RACHELMCADAMS | 13 | "Doctor Strange" actress who plays the title character's mom in 33-/49-Across: 2 wds. |
| 67% | VICTAYBACK | 10 | Actor who played diner owner Mel on the sitcom "Alice": 2 wds. |
| 67% | KALEYCUOCO | 10 | "The Flight Attendant" actress who voices the title character on HBO Max's animated "Harley Quinn": 2 wds. |
| 67% | ISABELSANFORD | 13 | Actress who played Louise Jefferson, the main character on the '70s sitcom "The Jeffersons" which is one of the longest-running sitcoms: 2 wds. |
| 67% | CHERYLHINES | 11 | Actress who plays the main character's ex-wife on "Curb Your Enthusiasm": 2 wds. |
| 65% | DONJOHNSON | 10 | "Miami Vice" actor who played the title character on 40-Across (2 wds.) |
| 65% | ALLISONJANNEY | 13 | Actress who plays Bonnie, the title mom on "Mom": 2 wds. |
| 64% | REBECCABREEDS | 13 | "Pretty Little Liars" actress who plays the title FBI agent on 34-Across (2 wds.) |
| 64% | CARRIEPRESTON | 13 | "The Good Wife" actress who plays the title role on the CBS spin-off of "The Good Wife," "Elsbeth" (2 wds.) |
| 63% | EDIE | 4 | Actress Falco who played the title character on "Nurse Jackie" |
| 63% | YARASHAHIDI | 11 | "The Sun Is Also a Star" actress who plays Zoey on the Freeform sitcom "Grown-ish": 2 wds. |
| 63% | OLIVIAMUNN | 10 | "The Predator" actress who plays the title role in "Violet": 2 wds. |