| 100% | ZOOEYDESCHANEL | 14 | Actress who portrays Jess on "New Girl": 2 wds. |
| 68% | MAXGREENFIELD | 13 | Actor who portrays Schmidt, one of Jess's loft-mates, on "New Girl": 2 wds. |
| 68% | LAMORNEMORRIS | 13 | Actor who portrays Winston, one of Jess's loft-mates, on "New Girl": 2 wds. |
| 61% | REBECCAROMIJN | 13 | "X-Men" actress who portrays a "Guardian" on 15-Across: 2 wds. |
| 60% | LYNDACARTER | 11 | Actress who portrayed 17- and 25-Across on TV from 1975 to 1979: 2 wds. |
| 59% | ALISONPILL | 10 | The actress who portrays Ivy Mayfair-Richards on "American Horror Story: Cult": 2 wds. |
| 59% | ZOOEYDESCHANEL | 14 | She plays Jess on "New Girl": 2 wds. |
| 57% | NATALIEDORMER | 13 | Actress who portrayed Margaery Tyrell on "Game of Thrones," who also plays Irene Adler, Holmes' former lover on "Elementary": 2 wds. |
| 56% | MAEWHITMAN | 10 | "Parenthood" actress who plays Annie Marks on "Good Girls": 2 wds. |
| 56% | KATEMCKINNON | 12 | "Ghostbusters" actress who portrayed Kellyanne Conway on "Saturday Night Live" (2 wds.) |
| 55% | ZOSIAMAMET | 10 | Actress who plays Shoshanna on "Girls": 2 wds. |
| 54% | AMYPOEHLER | 10 | "Parks and Recreation" actress who voices Duncan and Annie Harris on the new Fox animated series "Duncanville": 2 wds. |
| 54% | JENNIFERLOPEZ | 13 | Actress who portrayed Selena in "Selena": 2 wds. |
| 54% | KELLYBISHOP | 11 | Actress who plays Emily Gilmore on "Gilmore Girls" (2 wds.) |
| 54% | KELLYBISHOP | 11 | Actress who played Emily Gilmore on "Gilmore Girls" (2 wds.) |
| 53% | BRIELARSON | 10 | Actress who portrays Captain Marvel in "Avengers: Endgame": 2 wds. |
| 52% | ISABELSANFORD | 13 | Actress who played Louise on 15-Across: 2 wds. |
| 52% | SHELLEYFABARES | 14 | Actress who played Christine Armstrong on "Coach": 2 wds. |
| 52% | CAMILAMENDES | 12 | Actress who plays Veronica Lodge on "Riverdale": 2 wds. |
| 52% | MARISOLNICHOLS | 14 | Actress who plays Hermione Lodge on "Riverdale": 2 wds. |
| 52% | LAURENGRAHAM | 12 | Actress who played Sarah Braverman on "Parenthood": 2 wds. |
| 52% | KERIRUSSELL | 11 | "The Americans" actress who was on "The All-New Mickey Mouse Club": 2 wds. |
| 52% | REBECCAROMIJN | 13 | "X-Men" actress who plays Number One on "Strange New Worlds": 2 wds. |
| 52% | DIANAROSS | 9 | Actress who portrayed Billie Holiday in "Lady Sings the Blues": 2 wds. |
| 51% | JOANCUSACK | 10 | "Working Girl" actress who was nominated for five Emmys as Sheila Jackson on "Shameless": 2 wds. |
| 51% | CAROLKANE | 9 | "The Princess Bride" actress who plays Pelia on "Star Trek: Strange New Worlds": 2 wds. |
| 51% | KATHRYNHAHN | 11 | "Bad Moms" actress who portrays a governor in "Glass Onion": 2 wds. |
| 51% | JANELLEMONAE | 12 | "Moonlight" actress who portrays a tech entrepreneur in "Glass Onion": 2 wds. |
| 51% | OLIVIACOLMAN | 12 | "The Lobster" actress who portrayed Queen Anne in "The Favourite": 2 wds. |
| 50% | ELISABETHMOSS | 13 | "The Handmaid's Tale" actress who plays newspaper archivist Kirby Mazrachi on "Shining Girls": 2 wds. |