| 100% | ASTHMA | 6 | Affliction for which an inhaler may be prescribed |
| 51% | ANEMIA | 6 | Medical condition for which iron supplements may be prescribed |
| 46% | OCD | 3 | Condition for which Luvox may be prescribed, in brief |
| 43% | ADHD | 4 | Adderall may be prescribed for it, in brief |
| 42% | ADHD | 4 | Condition that Adderall may be prescribed for, in brief |
| 42% | XANAX | 5 | Drug that may be prescribed for anxiety and panic disorders |
| 42% | COW | 3 | Animal for which an arched-back yoga pose is named |
| 41% | SLOTMACHINE | 11 | For which 7-7-7 might be a jackpot |
| 41% | SALE | 4 | Event for which percentages may be specified |
| 41% | BRIE | 4 | It might be baked for an appetizer |
| 40% | LLAMA | 5 | Animal that may be mistaken for an alpaca |
| 40% | IPAD | 4 | Device on which an Apple Pencil may be used |
| 40% | CIG | 3 | What vape may be an alternative for, for short |
| 40% | BODYSHOP | 8 | It may be waiting for an accident to happen |
| 40% | TAJ | 3 | With 4-Down, mausoleum in India for which an Atlantic City casino was named |
| 39% | MAG | 3 | Something for which two eds may be better than one |
| 39% | KUNTAKINTE | 10 | Role for which LeVar Burton was nominated for an Emmy |
| 39% | TOKEN | 5 | What a quarter may be exchanged for at an arcade |
| 39% | BISCAY | 6 | Bay for which a French soup may have been named |
| 39% | UNESCO | 6 | Intl. grp. for which 47-Across was named an ambassador |
| 39% | ALI | 3 | 2001 biopic for which Will Smith got an Oscar nomination |
| 39% | YESNO | 5 | Like a question for which "maybe" is not an option |
| 39% | TONYA | 5 | Title role for which Margot Robbie was nominated for an Oscar |
| 39% | MSG | 3 | Ingredient that may be part of an “umami bomb,” for short |
| 39% | YESORNO | 7 | Type of question for which "maybe" is an unacceptable response: Hyph. |
| 39% | BLT | 3 | Lunchtime initialism to which an A, for avocado, is sometimes appended |
| 38% | ADORA | 5 | Sharp Objects role for which Patricia Clarkson was nominated for an Emmy |
| 38% | INFO | 4 | It may be symbolized by an "i" in a circle, for short |
| 38% | CSS | 3 | Language that might be used to create an 8-Down, for short |
| 38% | ASINGLEMAN | 10 | 2009 drama for which 21-Across was nominated for an Oscar: 3 wds. |