| 100% | NASA | 4 | Agency that launched space shuttles from 1981 to 2011: Abbr. |
| 58% | NASA | 4 | Agency that launched space shuttles: Abbr. |
| 56% | NASA | 4 | Agency that used to launch space shuttles: Abbr. |
| 51% | NASA | 4 | Agency that used to launch shuttles: Abbr. |
| 49% | NASA | 4 | Government agency that used to launch shuttle missions: Abbr. |
| 49% | NASA | 4 | Agency that's farming out the space shuttle to Boeing and SpaceX: Abbr. |
| 37% | NASA | 4 | Agency that launched the Curiosity rover: Abbr. |
| 37% | NASA | 4 | Agency that launched Voyager and Pioneer: Abbr. |
| 36% | NASA | 4 | US agency that launches satellites: Abbr. |
| 36% | NASA | 4 | Agency that launched the probe that photographed Pluto: Abbr. |
| 35% | NASA | 4 | US agency that launched the Mars rovers: Abbr. |
| 35% | USDA | 4 | Agency that assigns grades to beef: Abbr. |
| 35% | NASA | 4 | Agency that sent rovers to Mars: Abbr. |
| 34% | NASA | 4 | Agency that built the Hubble Space Telescope: Abbr. |
| 34% | NASA | 4 | Agency that uses the Kennedy Space Center: Abbr. |
| 34% | FBI | 3 | Agency that James Comey was fired from: Abbr. |
| 34% | NASA | 4 | Agency that sent people to the moon: Abbr. |
| 34% | IRS | 3 | Agency that some people send money to quarterly: Abbr. |
| 34% | NASA | 4 | Agency that's sent astronauts to the moon: Abbr. |
| 34% | NASA | 4 | US government agency that oversees the Launch Services Program: Abbr. |
| 33% | FDA | 3 | US health agency that gives its approval to edibles: Abbr. |
| 33% | COLUMBIA | 8 | Name of the first space shuttle, launched 1981 |
| 33% | NASA | 4 | US agency that sent rovers to Mars: Abbr. |
| 33% | NASA | 4 | Group that launches rockets from Cape Canaveral: Abbr. |
| 33% | NASA | 4 | Organization that developed space shuttles: Abbr. |
| 33% | SBA | 3 | US government agency that provides support to entrepreneurs: Abbr. |
| 32% | IRS | 3 | Agency that wants you to postmark your tax return by 4/15: Abbr. |
| 32% | NASA | 4 | Agency that plans to land a woman on the moon by 2024: Abbr. |
| 32% | NASA | 4 | Organization that sends missions to space: Abbr. |
| 31% | METEORITE | 9 | An object from space that falls to Earth |