| 100% | SHEPARD | 7 | Alan __; first American to travel to space |
| 78% | ALANSHEPARD | 11 | First American to travel into space (1961): 2 wds. |
| 75% | ALANSHEPARD | 11 | First American to travel into space during NASA's 1961 Freedom 7 mission |
| 68% | MAE | 3 | ___ Jemison, American astronaut who became the first African-American woman to travel to space in 1992 |
| 68% | SALLYRIDE | 9 | First American woman to travel into space (1983): 2 wds. |
| 68% | SALLYRIDE | 9 | The first American woman to travel to space |
| 67% | GAGARIN | 7 | First person to travel to space |
| 64% | EDWHITE | 7 | First American to walk in space |
| 63% | GRISSOM | 7 | First American to go into space twice |
| 62% | GAGARIN | 7 | Yuri, first man to travel into space |
| 56% | SHEPARD | 7 | Alan who was the first American in space |
| 54% | YURIGAGARIN | 11 | Russian who was the first person to travel into space and orbit the earth (1961): 2 wds. |
| 52% | EILEEN | 6 | ___ Collins, American astronaut who became the first woman to command a space shuttle mission in 1999 |
| 49% | SALLY | 5 | ___ Ride, American astronaut who became the first American woman to fly in space in 1983 |
| 49% | KALPANA | 7 | ___ Chawla, American astronaut who became the first Indian woman to fly in space in 1997 |
| 48% | WHITSON | 7 | Peggy ___, American astronaut who became the first woman to command the International Space Station in 2007 |
| 48% | GLENN | 5 | First American to orbit Earth |
| 47% | JOHNGLENN | 9 | First American to orbit the Earth |
| 47% | GLENN | 5 | First American to orbit the Earth |
| 47% | GGLLEENNNN | 10 | First American to orbit the earth |
| 46% | GRISSOM | 7 | Second American to fly in space |
| 46% | SHEPARD | 7 | First American in space |
| 45% | JOHNGLENN | 9 | First American to orbit the earth (1962): 2 wds. |
| 45% | GARN | 4 | Jake __, first Congressman to fly in space |
| 45% | GARN | 4 | Jake ___, first Congressman to fly in space |
| 45% | YURI | 4 | ___ Gagarin, first man to journey into space |
| 45% | LEONOV | 6 | Alexei __, first Russian to walk in space |
| 45% | JOHNGLENN | 9 | The first American to orbit the Earth |
| 45% | GLENN | 5 | John, first American to orbit the planet |
| 45% | SALLYRIDE | 9 | First American woman in space |