| 100% | BRAVENEWWORLD | 13 | Aldous Huxley novel on the ALA's Top Ten Challenged Books List for 2011: 3 wds. |
| 66% | BELOVED | 7 | Toni Morrison novel on the ALA's Top Ten Challenged Books List for 2012 |
| 66% | FOREVER | 7 | Judy Blume novel on the ALA's Top Ten Challenged Books List for 2005 |
| 60% | THEKITERUNNER | 13 | Khaled Hosseini novel on the American Library Association's Top Ten Challenged Books List for 2012: 3 wds. |
| 34% | BLUBBER | 7 | 1974 young adult novel by 45-Across that is #43 on the ALA's Top 100 Banned/Challenged Books (2000-2009) (2 wds.) |
| 34% | FOREVER | 7 | 1975 young adult novel by 45-Across that is #16 on the ALA's Top 100 Banned/Challenged Books (2000-2009) (2 wds.) |
| 34% | TIGEREYES | 9 | 1981 young adult novel by 45-Across that is #87 on the ALA's Top 100 Banned/Challenged Books (2000-2009) (2 wds.) |
| 28% | TENBIGONES | 10 | Novel in Janet Evanovich's 32-Across series that was published between "To the Nines" and "Eleven on Top" (3 wds.) |
| 27% | IMUP | 4 | "___ for the challenge." ("Bring it on."): 2 wds. |
| 26% | LONGTALLSALLY | 13 | 1956 Little Richard hit that's #55 on the Rolling Stone list: 3 wds. |
| 26% | GAMEOFTHRONES | 13 | Fantasy TV series based on the novels of George R. R. Martin: 3 wds. |
| 24% | IGOTTAFEELING | 13 | 2009 Black Eyed Peas song that was #1 on the Billboard Hot 100 for 14 weeks: 3 wds. |
| 24% | HARDTOLOVE | 10 | 2012 top 10 hit for Lee Brice (his first on the Hot Country chart): 3 wds. |
| 24% | AVNIDOSHI | 9 | American writer whose debut novel, "Burnt Sugar," was shortlisted for the 2020 Booker Prize (2 wds.) |
| 24% | BRANDONTAYLOR | 13 | American writer whose debut novel, "Real Life," was shortlisted for the 2020 Booker Prize (2 wds.) |
| 24% | UPTOIT | 6 | Ready for the challenge: 3 wds. |
| 24% | BRAVENEWWORLD | 13 | 2020 Peacock sci-fi series that was based on an Aldous Huxley novel: 3 wds. |
| 24% | BRUCEDESILVA | 12 | Novelist whose "Rogue Island" won the 2011 Edgar Award for Best First Novel (2 wds.) |
| 24% | AANDE | 5 | Original network for the series based on the 18-Across novels by 40-Across (3 wds.) |
| 23% | DIANECOOK | 9 | American writer whose debut novel, "The New Wilderness," was shortlisted for the 2020 Booker Prize (2 wds.) |
| 23% | YALE | 4 | It's #3 on the U.S. News and World Report list of top American universities |
| 23% | THELOCKARTIST | 13 | Steve Hamilton novel that won the 2011 Edgar Award for Best Novel (3 wds.) |
| 23% | OLDTOWNROAD | 11 | 2019 song by Lil Nas X which peaked at number one on the Billboard Hot 100 for nineteen consecutive weeks: 3 wds. |
| 23% | NICEST | 6 | Like the top names on Santa's list, perhaps |
| 23% | MARKHARMON | 10 | "NCIS" star tied for fourth (with Alec Baldwin) on Forbes' 2011-2012 Highest-Paid TV Actors list: 2 wds. |
| 23% | HUGHLAURIE | 10 | "House" star tied for second (with Ray Romano) on Forbes' 2011-2012 Highest-Paid TV Actors list: 2 wds. |
| 23% | THEFOGOFWAR | 11 | Documentary film based on Robert S. McNamara that won the Oscar for Best Documentary Feature in 2003: 4 wds. |
| 23% | MADEINAMERICA | 13 | "O.J.:___," documentary series, based on the life of O. J. Simpson, that won the Oscar for Best Documentary Feature in 2016: 3 wds. |
| 22% | MAKEITRAIN | 10 | Song on Pop Smoke's "Shoot for the Stars, Aim for the Moon" featuring Rowdy Rebel (3 wds.) |
| 22% | ANN | 3 | Word on the Big Ten city list |