| 100% | TRIXIE | 6 | Alice's best friend on "The Honeymooners" |
| 72% | MORDECAI | 8 | Rigby's best friend on the Regular Show |
| 64% | CARL | 4 | Lenny's best friend on "The Simpsons" |
| 62% | RHODA | 5 | Mary's best friend on the CBS sitcom "The Mary Tyler Moore Show" starring Mary Tyler Moore and Valerie Harper |
| 62% | RAJ | 3 | Howard's best friend on "The Big Bang Theory" |
| 62% | IRIS | 4 | *Barry's best friend, on "The Flash" |
| 62% | WILMA | 5 | Betty's best friend, on "The Flintstones" |
| 62% | BART | 4 | Milhouse's best friend, on "The Simpsons" |
| 60% | BERT | 4 | Ernie's best friend on "Sesame Street" for whom Ernie dedicated the song "That's What Friends Are For" |
| 58% | CHALK | 5 | I am a teacher's best friend. I help them write on the blackboard. Who am I? |
| 56% | RALPH | 5 | Alice’s hubby on “The Honeymooners” |
| 56% | JOEY | 4 | Chandler's best friend on "Friends" |
| 56% | ELAINE | 6 | Jerry's best friend on "Seinfeld" |
| 56% | ABED | 4 | Troy's best friend on "Community" |
| 56% | ISSA | 4 | Molly’s best friend on “Insecure” |
| 55% | NED | 3 | Jimbo's best friend on "South Park" |
| 55% | BLAIR | 5 | Serena's best friend on "Gossip Girl" |
| 55% | JENNA | 5 | Liz's best friend on "30 Rock" |
| 55% | OTIS | 4 | Eric's best friend on "Sex Education" |
| 54% | RHODA | 5 | Mary's best friend on 70's TV |
| 54% | MAX | 3 | Caroline's best friend on "2 Broke Girls" |
| 54% | ETHEL | 5 | Lucy's best friend on "I Love Lucy" |
| 54% | TITUS | 5 | Kimmy's best friend on "Unbreakable Kimmy Schmidt" |
| 54% | ANN | 3 | Leslie's best friend on "Parks and Recreation" |
| 54% | ALICE | 5 | Trixie's best friend, on TV |
| 54% | BART | 4 | Milhouse's best friend, on TV |
| 54% | NORM | 4 | Cliff's best friend, on "Cheers" |
| 54% | GEORGECOSTANZA | 14 | Character who is Jerry's best friend since high school and is played by Jason Alexander on the show "Seinfeld": 2 wds. |
| 54% | CECE | 4 | Jess's best friend on TV's "New Girl" |
| 54% | ELMO | 4 | One of Zoe's best friends on "Sesame Street" |