| 100% | IVES | 4 | American composer who pioneered in polytonality |
| 45% | MENDEL | 6 | Gregor who pioneered in genetics |
| 45% | EMILEZOLA | 9 | Writer who pioneered in naturalism |
| 45% | ENO | 3 | Brian who pioneered in ambient music |
| 45% | ROSA | 4 | Parks who pioneered in civil rights |
| 45% | ARP | 3 | Artist Jean who pioneered in Dadaism |
| 45% | EULER | 5 | Swiss mathematician who pioneered in calculus |
| 45% | EULER | 5 | Swiss who pioneered in graph theory |
| 45% | VERNE | 5 | Jules who pioneered in science fiction |
| 45% | DIRAC | 5 | Paul who pioneered in quantum mechanics |
| 45% | MOOG | 4 | Robert who pioneered in electronic music |
| 44% | WEUGENESMITH | 12 | American photojournalist and pioneer in photo-essays who is known for his brutally vivid World War II photographs: 3 wds. |
| 44% | SIENNAMILLER | 12 | "American Woman" actress who plays a pioneer woman in "Horizon: An American Saga - Chapter 1" (2 wds.) |
| 44% | PAULDIRAC | 9 | Physics Nobelist who pioneered in quantum mechanics |
| 44% | BINET | 5 | Alfred who pioneered in I.Q. testing |
| 43% | TAIT | 4 | Mathematical physicist Peter who pioneered in knot theory |
| 43% | ARDEN | 5 | Elizabeth who pioneered in the advertising of beauty aids |
| 43% | FERMAT | 6 | French mathematician who pioneered in the theory of probability |
| 42% | ERNST | 5 | With 31-Down, Viennese-born photographer who pioneered in journalism |
| 42% | EULER | 5 | 18th-century mathematician who pioneered in graph and number theory |
| 42% | MOZART | 6 | Composer who wrote the Prague Symphony in 1786 |
| 41% | IVES | 4 | James Merritt ___, pioneer in American lithography |
| 41% | SOUSA | 5 | Composer who, as it happens, died in March (1932) |
| 41% | GARDNER | 7 | American actress who starred in Mogambo, Ava __ |
| 41% | WILLACATHER | 11 | Pioneering woman in American literature? |
| 40% | VIRGILTHOMSON | 13 | American composer of "Four Saints in Three Acts": 2 wds. |
| 40% | HESSE | 5 | Sculptor Eva who pioneered postminimalism in the 1960s |
| 40% | GERSHWIN | 8 | Composer of An American in Paris |
| 40% | MARC | 4 | ___ Shaiman, American composer who has been nominated seven times for the Academy Awards |
| 39% | JAMESDEAN | 9 | American actor who died prematurely in 1955 |