| 100% | GWENJORGENSEN | 13 | American distance runner and two-time ITU World Champion who was the first to win a triathlon gold for USA in the Olympics: 2 wds. |
| 43% | JIMTHORPE | 9 | American athlete who won a gold for decathlon at the 1912 Olympics, and has spent 7 years in MLB and 13 in APFA (now NFL): 2 wds. |
| 43% | ANNPRESTON | 10 | American physician and activist who was the first female dean of a medical school in the world: 2 wds. |
| 43% | YUTOHORIGOME | 12 | Japanese skateboarder who was the first person to win a gold medal in skateboarding at the Olympics, in men's street skateboarding in Tokyo in 2021 (2 wds.) |
| 42% | EDITHWHARTON | 12 | 13-Across and 25-Across writer who was the first woman to win a Pulitzer Prize in Literature, for her 1920 novel "The Age of Innocence" (2 wds.) |
| 41% | WAYNEGRETZKY | 12 | Hockey legend who was the first since Bobby Orr to tally 100+ assists in a season, and did so 11 times: 2 wds. |
| 40% | STEFFIGRAF | 10 | Tennis player who is the only player (man or woman) to win a Grand Slam and Olympic gold medal in one year: 2 wds. |
| 40% | CATEBLANCHETT | 13 | "Blue Jasmine" and "The Aviator" star who was the first Australian to win Oscars in two acting categories (2 wds.) |
| 40% | TONIMORRISON | 12 | "Beloved" author who died August 5, and who was the first African-American woman to win a Nobel Prize: 2 wds. |
| 39% | SEATTLESLEW | 11 | 1977 Triple Crown winner who was the first American champion to have been undefeated in previous races: 2 wds. |
| 39% | CASEYSTONER | 11 | Australian motorcycle racer and two-time MotoGP World Champion, who raced for Ducati and Honda and is considered one of the best: 2 wds. |
| 39% | JIMTHORPE | 9 | NFL player who won two gold medals in the 1912 Olympics, and a charter member of the Pro Football Hall of Fame: 2 wds. |
| 39% | RUDOLPH | 7 | Wilma ___, late American sprinter who was the first American woman to win three gold medals in a single Olympic Games |
| 39% | SAMSMITH | 8 | "Stay With Me" singer who was a first-time Grammy nominee for Record of the Year (and won): 2 wds. |
| 39% | ETHELWATERS | 11 | Harlem Renaissance singer and actress who was the first African American to star in her own TV show: 2 wds. |
| 39% | NICOLEKIDMAN | 12 | "Moulin Rouge!" and "The Hours" star who was the first Australian to win an Oscar for Best Actress and the first to be nominated in consecutive years (2 wds.) |
| 39% | CAROLEKING | 10 | "You've Got a Friend" singer/pianist who was the first woman to win a Grammy for Song of the Year (2 wds.) |
| 38% | EVELYNASHFORD | 13 | The first track and field athlete to run 100 meters under 11 seconds in an Olympic Games and who has won a total of 5 Olympic medals: 2 wds. |
| 38% | CHASEHEADLEY | 12 | Yankees third baseman who, in 2012, won a Gold Glove, a Silver Slugger Award and was also the NL RBI leader, playing for the Padres : 2 wds. |
| 38% | ROSIEODONNELL | 13 | "The Flintstones" actress and comedian who won $500,000 for charity on "Who Wants to Be a Millionaire" in 2000: 2 wds. |
| 38% | MARIONJONES | 11 | American track star who won three gold medals and two bronze medals at the Summer Olympics in Sydney in 2000 (2 wds.) |
| 38% | JORDANSPIETH | 12 | American golfer who won the 2017 Open Championship and was runner-up to 49-Across in the 2021 Open Championship (2 wds.) |
| 38% | FERNANDO | 8 | Spanish Formula One driver Alonso, who currently drives for McLaren-Honda, and is a two-time World Champion : 2 wds. |
| 38% | GEOFFREYRUSH | 12 | "Shine" star who was the first Australian to be nominated for Oscars in two acting categories (2 wds.) |
| 37% | JOHNSALLEY | 10 | First NBA player to win a championship in three different decades and who is also a vegan activist: 2 wds. |
| 37% | SHOHEIOHTANI | 12 | Japanese MLB player who was the first player in history to be a pitcher and hitter in the All-Star Game, in 2021: 2 wds. |
| 37% | MICHAELPHELPS | 13 | American retired competitive swimmer who won a record eight gold medals at the 2008 Olympic Games and is considered the greatest swimmer ever: 2 wds. |
| 37% | KATHRYNSMITH | 12 | American football coach who has been actively involved as a full-time female coach in NFL history and has most recently served for the Buffalo Bills: 2 wds. |
| 36% | FRANKLANGELLA | 13 | "The Americans" actor who won two Tony Awards for Best Actor in a Play, for "Frost/Nixon" and "The Father" (2 wds.) |
| 36% | NORMMACDONALD | 13 | "SNL" actor and comedian who won $500,000 for charity on "Who Wants to Be a Millionaire" in 2000: 2 wds. |