| 100% | AGT | 3 | American reality show created by Simon Cowell: Abbr. |
| 83% | AGT | 3 | American talent show created by Simon Cowell: Abbr. |
| 66% | FACTOR | 6 | "The X ___" (reality show created by Simon Cowell) |
| 58% | XFACTOR | 7 | Competition show created by Simon Cowell, with "The" (2 wds.) |
| 57% | AGT | 3 | American reality show judged by Howie Mandel: Abbr. |
| 54% | AGT | 3 | Simon Cowell's reality show: Abbr. |
| 53% | IDOL | 4 | "American ___" (TV show created by Simon Fuller) |
| 52% | AGT | 3 | Simon Cowell and Howie Mandel's reality show: Abbr. |
| 51% | AGT | 3 | Reality show where Simon Cowell and Howie Mandel serve as judges: Abbr. |
| 48% | ANTM | 4 | Reality show created by Tyra Banks, for short |
| 47% | DIRECTION | 9 | British band created by Simon Cowell: One __ |
| 46% | TALENT | 6 | "America's Got ___" (TV competition created by Simon Cowell) |
| 44% | AGT | 3 | Reality show currently hosted by Terry Crews: Abbr. |
| 43% | SNL | 3 | Sketch comedy show created by Lorne Michaels: Abbr. |
| 43% | SNL | 3 | NBC sketch show created by Lorne Michaels: Abbr. |
| 43% | SNL | 3 | NBC show created by Lorne Michaels: Abbr. |
| 42% | AGT | 3 | Reality show judged by Heidi Klum and Sofia Vergara: Abbr. |
| 41% | SURVIVOR | 8 | American reality show hosted by Jeff Probst, where contestants are marooned in an isolated location |
| 40% | THEXFACTOR | 10 | Music competition series created by Simon Cowell that featured 53-Across as a host in 2012 and 2013 (3 wds.) |
| 40% | THEVOICE | 8 | American reality show hosted by Carson Daly, which works in a format similar to 21-Across: 2 wds. |
| 39% | AGT | 3 | Reality competition show hosted by Terry Crews: Abbr. |
| 38% | XFACTOR | 7 | The __, TV talent show devised by Simon Cowell |
| 38% | AMERICANIDOL | 12 | American reality show hosted by Ryan Seacrest, where contestants compete to be the best singer, chosen by the viewers: 2 wds. |
| 37% | GIRLS | 5 | Show created by Lena Dunham |
| 36% | RACE | 4 | "The Amazing ___," American reality show |
| 35% | LALAW | 5 | TV show created by Steven Bochco |
| 35% | WWERAW | 6 | TV show created by Vince McMahon |
| 35% | GIRLS | 5 | HBO show created by Lena Dunham |
| 35% | THEVIEW | 7 | TV show created by Barbara Walters |
| 34% | ATLANTA | 7 | Hit TV show created by Donald Glover |