| 100% | LUKEAIKINS | 10 | American skydiver who was the first to land safely without a parachute or wingsuit from mid-tropospheric altitude: 2 wds. |
| 35% | ETHELWATERS | 11 | Harlem Renaissance singer and actress who was the first African American to star in her own TV show: 2 wds. |
| 34% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 34% | SEATTLESLEW | 11 | 1977 Triple Crown winner who was the first American champion to have been undefeated in previous races: 2 wds. |
| 34% | JOANRIVERS | 10 | Comedian who was the first woman to host a late-night talk show on a major network: 2 wds. |
| 34% | MARTHAGRAHAM | 12 | American dancer who was the first dancer to perform at the White House and to receive the Presidential Medal of Freedom: 2 wds. |
| 33% | LORNASIMPSON | 12 | "Projects 23" photographer who was the first African-American woman to have a solo exhibition at the Museum of Modern Art (2 wds.) |
| 33% | WAYNEGRETZKY | 12 | Hockey legend who was the first since Bobby Orr to tally 100+ assists in a season, and did so 11 times: 2 wds. |
| 33% | ALTHEAGIBSON | 12 | Tennis great who was the first person of color to win a Wimbledon championship (2 wds.) |
| 33% | GWENJORGENSEN | 13 | American distance runner and two-time ITU World Champion who was the first to win a triathlon gold for USA in the Olympics: 2 wds. |
| 33% | SHOHEIOHTANI | 12 | Japanese MLB player who was the first player in history to be a pitcher and hitter in the All-Star Game, in 2021: 2 wds. |
| 33% | MOMSMABLEY | 10 | Trailblazing African American who was the first female comedian to perform at the Apollo Theater: 2 wds. |
| 33% | JACKIESTILES | 12 | 2016 Women's Basketball Hall of Fame inductee who was the first Division I player to score over 1,000 points in a season: 2 wds. |
| 32% | ANNPRESTON | 10 | American physician and activist who was the first female dean of a medical school in the world: 2 wds. |
| 32% | STEFFIGRAF | 10 | Tennis player who is the only player (man or woman) to win a Grand Slam and Olympic gold medal in one year: 2 wds. |
| 31% | BOBBYFISCHER | 12 | American-born chess master who was the World Champion from 1972 to 1975: 2 wds. |
| 31% | ETHEL | 5 | Waters who was the first Black American to host a national television show |
| 31% | POITIER | 7 | Sidney who was the first African American to win a Best Actor Oscar |
| 31% | PATSYCLINE | 10 | American singer (birthday today) who was the first female solo artist inducted to the Country Music Hall of Fame: 2 wds. |
| 31% | JOSECANSECO | 11 | Retired ballplayer who was the first to hit 40 homers and steal 40 bases in the same season: 2 wds. |
| 31% | MICHAELSTEELE | 13 | American bassist who was a part of one of the first all-female rock groups, "The Bangles" that created hits like "Manic Monday": 2 wds. |
| 31% | ITO | 3 | Olympic skater who was the first woman to land a triple axel in competition |
| 31% | ITO | 3 | Skater Midori who was the first woman to land a triple axel in competition |
| 31% | TONIMORRISON | 12 | "Beloved" author who died August 5, and who was the first African-American woman to win a Nobel Prize: 2 wds. |
| 31% | AMELIAEARHART | 13 | Aviation pioneer who was the first woman to fly solo across the Atlantic: 2 wds. |
| 31% | SHERYLSWOOPES | 13 | Openly gay basketballer who was the first woman to be signed by the WNBA: 2 wds. |
| 31% | TENZINGYATSO | 12 | 14th Dalai Lama who was the first Tibetan to win the Nobel Peace Prize: 2 wds. |
| 31% | HARLANCOBEN | 11 | 17-Across and 30-Across novelist who is the first writer to win an Anthony Award, a Shamus Award, and an Edgar Award (2 wds.) |
| 30% | WARRENMOON | 10 | Undrafted quarterback who was the first African American quarterback inducted into the Hall of Fame: 2 wds. |
| 30% | LAURABUSH | 9 | Former Girl Scout who was First Lady of the United States from 2001 to 2009 (2 wds.) |