| 100% | MONA | 4 | Angela's mother (played by Katherine Helmond) on "Who's the Boss?" |
| 50% | ETHEL | 5 | Muggs who was played by Shannon Purser on The CW's "Riverdale" |
| 50% | TONYDANZA | 9 | "The Good Cop" actor who played a former pro baseball player on "Who's the Boss?": 2 wds. |
| 48% | MARY | 4 | ___ Morstan, Watson's wife in the Sherlock Holmes stories who was played by Amanda Abbington on screen |
| 47% | CONSTANCEWU | 11 | Actress who plays 36-Across's mother on "Fresh off the Boat" (2 wds.) |
| 46% | DEANNATROI | 10 | "Star Trek" character played by Marina Sirtis, who serves as the ship's counselor on USS Enterprise-D: 2 wds. |
| 45% | GEORGECOSTANZA | 14 | Character who is Jerry's best friend since high school and is played by Jason Alexander on the show "Seinfeld": 2 wds. |
| 44% | IRENE | 5 | ___ Adler, iconic character from the Sherlock Holmes stories who was played by Lara Pulver on screen |
| 43% | MARSHA | 6 | Actress Mason who plays Frankie's mother on "The Middle" |
| 43% | DIANE | 5 | ___ Chambers, character on the TV show "Cheers" who was played by Shelley Long |
| 43% | SAM | 3 | ___ Malone, character on the TV show "Cheers" who was played by Ted Danson |
| 42% | MICHAELDAWSON | 13 | The father who is trying to recover his son on "Lost," played by Harold Perrineau: 2 wds |
| 42% | EMMYROSSUM | 10 | "Shameless" actress who plays Danny's mother on "The Crowded Room": 2 wds. |
| 42% | DALE | 4 | Character who was played by Jeffrey DeMunn on "The Walking Dead" |
| 41% | MAC | 3 | The name of the character played by Rob McElhenney on "It's Always Sunny in Philadelphia" |
| 41% | LAURIEMETCALF | 13 | "The Conners" actress who played Sheldon's mother on "The Big Bang Theory" (2 wds.) |
| 41% | JUNELOCKHART | 12 | Actress of the month who played the mother on "Lassie": 2 wds. |
| 41% | HARP | 4 | Instrument played by Sheila Bromberg on the Beatles' "She's Leaving Home" |
| 41% | ANGELA | 6 | Tony's boss on "Who's the Boss?" |
| 41% | DELLA | 5 | With 37-Across, "Touched by an Angel" actress who played a landlady on "Chico and the Man" |
| 41% | MONA | 4 | "Who's the Boss?" mother |
| 41% | KATHYBATES | 10 | "American Horror Story" actress who played Amy's mother on "The Big Bang Theory" (Abbr.) |
| 41% | SUSANCLARK | 10 | Actress who played the adoptive mother on the 1980s sitcom "Webster": 2 wds. |
| 41% | JERRYVANDYKE | 12 | "My Mother the Car" actor who plays Luther on 60-Across (3 wds.) |
| 41% | ABBI | 4 | Comedian Jacobson who plays a character by the same name on "Broad City" |
| 41% | ARCHIEANDREWS | 13 | Comics character played by KJ Apa on The CW's "Riverdale" (2 wds.) |
| 41% | BETTYCOOPER | 11 | Comics character played by Lili Reinhart on The CW's "Riverdale" (2 wds.) |
| 41% | VERONICALODGE | 13 | Comics character played by Camila Mendes on The CW's "Riverdale" (2 wds.) |
| 40% | HEIGL | 5 | Katherine who played Izzie Stevens on "Grey's Anatomy" |
| 40% | KATEYSAGAL | 10 | "Sons of Anarchy" actress who played Penny's mother on "The Big Bang Theory" (2 wds.) |