| 100% | PREDATOR | 8 | Animal with a natural instinct to hunt and kill |
| 42% | GOAT | 4 | Domestic animal related to sheep, with horns and a beard |
| 41% | PREYS | 5 | Hunts and kills another animal |
| 40% | ELEPHANT | 8 | Animal with a trunk and tusks |
| 40% | GNU | 3 | Animal with a mane and a beard |
| 40% | ASS | 3 | Animal with a "burden" to carry |
| 39% | COATI | 5 | Animal with a long snout and striped tail |
| 38% | GOAT | 4 | Animal with horns and a beard |
| 38% | BEAR | 4 | Animal with a polar, brown, and sloth variety |
| 37% | ANTEATER | 8 | Animal with long nose and tongue to devour insects |
| 37% | GOAT | 4 | Farm animal with horns and a beard |
| 36% | OKAPI | 5 | African animal with features similar to zebras and giraffes |
| 36% | OTTER | 5 | Sea animal with "pockets" to store food and tools |
| 36% | DOLPHIN | 7 | Animal with a sophisticated language of whistles and clicks |
| 36% | KINGDOM | 7 | Animal __, a division to classify natural objects |
| 36% | OVERWATER | 9 | To kill a plant with excessive H2O |
| 35% | CATS | 4 | "Raining ___ and dogs," idiom with a natural phenomenon that is used to describe torrential weather |
| 35% | NONO | 4 | Eating pizza with a fork and knife, to New Yorkers |
| 35% | HIPPO | 5 | Animal with some similar features to a rhino |
| 35% | FOURHCLUBS | 10 | Youth groups ... with a hint to 17-, 28- and 44-Across |
| 35% | WHIP | 4 | Beat food with a whisk to incorporate air and produce volume |
| 35% | WAINSCOT | 8 | To line a room with wooden boards and panels |
| 34% | FACE | 4 | "___ like thunder," British idiom with a natural phenomenon that is used to describe a furious person |
| 34% | ARTCENTER | 9 | Place with a gallery, and a hint to this puzzle's theme |
| 34% | WHATSTHEMATTER | 14 | Question of concern, with a hint to 20-, 25- and 43-Across |
| 34% | FINDINGNEMO | 11 | 2003 animated film … with a hint to 17-, 32- and 41-Across |
| 34% | ONOFFSWITCH | 11 | Electrical device with a hint to answering 17-, 27- and 48-Across |
| 34% | THEBIGFIVEOH | 12 | Milestone birthday, informally ... with a hint to 20-, 31- and 41-Across |
| 34% | AHAMOMENT | 9 | Sudden insight ... with a hint to 17-, 24-, 40- and 50-Across |
| 34% | PET | 3 | Animal that goes to the vet and rhymes with "vet" |