| 100% | NEUTRON | 7 | Animated boy genius, Jimmy __ |
| 75% | NEUTRON | 7 | This Jimmy is an animated boy genius |
| 59% | NEUTRON | 7 | Jimmy, the Boy Genius |
| 53% | NEUTRON | 7 | Surname of Jimmy, Boy Genius |
| 47% | TOMSWIFT | 8 | Boy genius of juvenile fiction |
| 46% | TOMSWIFT | 8 | Boy genius of young adult fiction |
| 46% | TOMSWIFT | 8 | Boy genius of old teen fiction |
| 46% | DEXTER | 6 | Boy genius with a secret laboratory |
| 42% | TATE | 4 | Title boy genius of a 1991 film |
| 40% | TOMSWIFT | 8 | Boy genius of early-1900s teen fiction created by Edward Stratemeyer |
| 40% | DEXTER | 6 | Cartoon boy genius with a sister named Dee Dee |
| 40% | FAMILYGUY | 9 | Animated series with genius baby, talking dog |
| 38% | DEXTER | 6 | The boy genius who has a hidden lab in his room |
| 38% | ARLO | 4 | "___ the Alligator Boy" (2021 Netflix animated film) |
| 38% | AND | 3 | "The Boy ___ the Heron" (2023 animated movie) |
| 37% | ANDREAMARTIN | 12 | "Jimmy Neutron: Boy Genius" voice actress who plays Aunt Voula in "My Big Fat Greek Wedding 3" (2 wds.) |
| 36% | ARLO | 4 | "Alligator Boy" in a 2021 Netflix animated film |
| 35% | ARLO | 4 | "I Heart ___" (Netflix animated series about an "alligator boy") |
| 31% | HEA | 3 | "Ain't ___ Genius" (Jimmy Buffett song) |
| 31% | HEA | 3 | "Ain't ___ Genius" (Jimmy Buffett tune) |
| 31% | HEA | 3 | Ain't ___ Genius? (Jimmy Buffett song) |
| 31% | MANDARK | 7 | Dexter's equally genius rival in the animated TV series, "Dexter's Laboratory" |
| 31% | SONG | 4 | "___ of the Sea," 2014 animated ocean movie about a boy and his sister |
| 31% | RICH | 4 | "Richie ___," animated show produced by Hanna-Barbera which is about a wealthy boy |
| 29% | DEXTERSLABORATORY | 17 | Cartoon Network show about a boy-genius inventor |
| 28% | LAB | 3 | Domain of the cartoon boy-genius Dexter, for short |
| 28% | EDEDDNEDDY | 10 | Animated comedy featuring three preteen boys that's the longest-running original series on 45-Across (4 wds.) |
| 28% | ISLEOFDOGS | 10 | 2018 Wes Anderson stop-motion animated film about a boy looking for his pet (3 wds.) |
| 28% | COCO | 4 | Pixar film about a boy mariachi that won the 2018 Annie Award for Best Animated Feature |
| 27% | ALIVE | 5 | Animated |