| 100% | FOUNDATION | 10 | Apple TV+ series about the Galactic Empire starring Lee Pace, 16-Across/18-Across and 34-Across/36-Across based on sci-fi novels by Isaac Asimov |
| 41% | BADMONKEY | 9 | 2024 Apple TV+ series starring Michelle Monaghan, 15-Across, and 26-Across based on the 2013 novel by 33-Across (2 wds.) |
| 36% | THENIGHTAGENT | 13 | Netflix action thriller series starring 18-Across and Luciane Buchanan based on the novel of the same name by 40-Across (3 wds.) |
| 35% | ALTEREDCARBON | 13 | American dystopian sci-fi TV series starring Joel Kinnaman which is based on a novel of the same name by Richard K. Morgan: 2 wds. |
| 35% | NAKEDSUN | 8 | "The ___," 1957 sci-fi novel by Isaac Asimov that was adapted into an episode of the TV series "Out of the Unknown": 2 wds. |
| 35% | ALMOSTFAMILY | 12 | Fox TV drama starring 18-Across and 32-Across based on the Australian series "Sisters" (2 wds.) |
| 33% | SERPENT | 7 | "The Essex ___," series based on Sarah Perry's eponymous novel, starring Claire Danes and Tom Hiddleston on Apple TV+ |
| 32% | PACHINKO | 8 | Apple TV+ drama about a Korean family in Japan, based on a novel by Min Jin Lee |
| 32% | ELEMENTARY | 10 | TV series starring Jonny Lee Miller and Lucy Liu based on the fictional detective at 15a |
| 31% | STARTREKPICARD | 14 | Sci-fi series starring 16-Across and 34-Across that debuted on CBS All Access on January 23, 2020 (3 wds.) |
| 30% | SWEETBITTER | 11 | American drama TV series starring Ella Purnell which is based on a novel of the same name by Stephanie Danler |
| 30% | GOODOMENS | 9 | Amazon series starring 15-Across/17-Across and 45-Across/47-Across based on a novel by Terry Pratchett and Neil Gaiman (2 wds.) |
| 30% | GREYHOUND | 9 | 2020 war film starring Tom Hanks, 15-Across, 21-Across, and 38-Across based on the novel "The Good Shepherd" by C.S. Forester |
| 30% | THEALIENIST | 11 | American period drama TV series starring Dakota Fanning which is based on a novel of the same name by Caleb Carr: 2 wds. |
| 30% | DISCLAIMER | 10 | Apple TV+ series based on a novel by Renée Knight |
| 30% | AFTERPARTY | 10 | "The ___," series about a high school reunion, starring Tiffany Haddish and Sam Richardson on Apple TV+ |
| 30% | DOME | 4 | "Under the ___," 2013 sci-fi mystery TV series based on Stephen King's eponymous novel |
| 29% | SHOW | 4 | "The Morning ___," series about a breakfast news program, starring Jennifer Aniston and Reese Witherspoon on Apple TV+ |
| 29% | AANDE | 5 | Original network for the series based on the 18-Across novels by 40-Across (3 wds.) |
| 29% | BIG | 3 | With 60-Across, TV crime series based on the novel "The Highway" by C.J. Box |
| 29% | PIECESOFHER | 11 | Netflix series starring 17-Across, 29-Across, and Bella Heathcote based on a novel by Karin Slaughter (3 wds.) |
| 29% | TRIPODS | 7 | The —, 1980s BBC TV series based on novels by John Christopher |
| 29% | DOOR | 4 | "The Shrink Next ___," series about a psychiatrist who violates conventions, starring Will Ferrell and Paul Rudd on Apple TV+ |
| 28% | LANE | 4 | "Firefly ___," show starring Katherine Heigl and Sarah Chalke as friends that is based on the eponymous novel by Kristin Hannah |
| 28% | BUPKIS | 6 | TV series created by and starring Pete Davidson that is based on his life |
| 28% | OUTLANDER | 9 | Fantasy TV series based on novels of the same name by Diana Gabaldon |
| 28% | SEVERANCE | 9 | Series about workers whose memories have been surgically divided, starring Adam Scott and Britt Lower on Apple TV+ |
| 28% | WIND | 4 | The —, 1928 film starring Lillian Gish and Lars Hanson based on a novel by Dorothy Scarborough |
| 28% | AMERICA | 7 | "Little ___," anthology series about immigrants, starring Suraj Sharma and Zachary Quinto on Apple TV+ |
| 28% | ETERNITY | 8 | "The End of ___," 1955 sci-fi novel by Isaac Asimov that was shortlisted for the Hugo Award for Best Novel |