| 100% | EVAPERON | 8 | Argentine leader played by Patti LuPone and Madonna (2 wds.) |
| 76% | EVAPERON | 8 | Leader portrayed by Patti LuPone and Madonna (2 wds.) |
| 63% | EVITA | 5 | Argentine icon played by Madonna and Patti LuPone |
| 51% | EVITA | 5 | Musical role played by Madonna on film and Patti LuPone on Broadway |
| 44% | MALCOLMX | 8 | Civil rights leader played by Denzel Washington in a 1992 biopic: 2 wds. |
| 44% | RICHARDKIMBLE | 13 | Role played by 18- and 44-Across: 2 wds. |
| 41% | MALCOLMX | 8 | Black Nationalist leader played by Denzel Washington (2 wds.) |
| 41% | EVITA | 5 | Role for Patti LuPone and Madonna |
| 41% | NEWTSCAMANDER | 13 | Character played by 15-Across in "Fantastic Beasts and Where to Find Them": 2 wds. |
| 40% | VITOCORLEONE | 12 | Mafia don played by both 14-Across and 28-Across in the "Godfather" franchise: 2 wds. |
| 39% | LEXLUTHOR | 9 | Superman nemesis played by Gene Hackman and Jesse Eisenberg: 2 wds. |
| 39% | WINTERSTALE | 11 | "The ___" play by William Shakespeare that has named characters Leontes and Polixenes from Sicilia and Bohemia respectively: 2 wds. |
| 38% | DWIGHTSCHRUTE | 13 | A character from "The Office" played by Rainn Wilson, who is the nemesis and eventual friend of 42a: 2 wds |
| 38% | EVITA | 5 | Argentine idol played by Madonna |
| 37% | MAMAROSE | 8 | Infamous stage mom famously played by Bernadette Peters and Patti LuPone |
| 37% | SARAHCONNOR | 11 | Heroic mother played by Linda Hamilton, Lena Headey, and Emilia Clarke (2 wds.) |
| 37% | JACKFROST | 9 | Wintery guy played by 15-Across, 24-Across, and 29-Across (2 wds.) |
| 37% | COSMOKRAMER | 11 | Character played by Michael Richards in "Seinfeld", who is 32-Across's neighbor and is often called a "hipster doofus": 2 wds. |
| 37% | MURPHYBROWN | 11 | CBS TV character with a colorful last name, played by Candice Bergen from 1988 to 1998 and 2018 to 2019: 2 wds. |
| 37% | PHILIPMARLOWE | 13 | Raymond Chandler detective played by Humphrey Bogart, Elliott Gould, and Robert Mitchum (2 wds.) |
| 37% | NEROWOLFE | 9 | Rex Stout detective played by Maury Chaykin, William Conrad, and Thayer David (2 wds.) |
| 37% | HERCULEPOIROT | 13 | Agatha Christie detective played by Kenneth Branagh, Peter Ustinov, and Albert Finney (2 wds.) |
| 36% | THEJOKER | 8 | Batman foe played by Cesar Romero, Jack Nicholson, Heath Ledger, and Jared Leto (2 wds.) |
| 36% | ALFIESOLOMONS | 13 | "Peaky Blinders" character, played by Tom Hardy, who ran a distillery and was seen on the show from season 2 till 4: 2 wds. |
| 36% | THIRDBASEMAN | 12 | Position played by 27-Across: 2 wds. |
| 36% | CENTERFIELD | 11 | Position played by 39-Across: 2 wds. |
| 36% | LEFTWING | 8 | Position played by 31-Across: 2 wds. |
| 36% | SHOOTINGGUARD | 13 | Position played by 18-Across: 2 wds. |
| 36% | JESSEPINKMAN | 12 | Character played by Aaron Paul in "Breaking Bad", who was a crystal meth dealer and worked with the character played by 30-Across: 2 wds. |
| 36% | JACKRYAN | 8 | CIA politico played by a Baldwin brother, Harrison Ford, Ben Affleck, and Chris Pine (2 wds.) |