| 100% | JOANNABRADY | 11 | Arizona-based sheriff/sleuth in a J.A. Jance book series (2 wds.) |
| 54% | HANNAHSWENSEN | 13 | Minnesota-based baker/sleuth in a Joanne Fluke book series (2 wds.) |
| 52% | STEPHANIEPLUM | 13 | New Jersey-based bounty hunter/sleuth in a Janet Evanovich book series (2 wds.) |
| 49% | TRUEBLOOD | 9 | HBO show based on a series of Charlaine Harris books: 2 wds. |
| 48% | WALTLONGMIRE | 12 | Sheriff of the fictional county of Absaroka, Wyoming, who is featured in 20 books by 40-Across and a 2012-2017 television series (2 wds.) |
| 46% | ALTEREDCARBON | 13 | Netflix series, based on a cyberpunk novel, set more than 300 years in the future: 2 wds. |
| 45% | KATHRYNHAHN | 11 | "WandaVision" actress who plays advice columnist Clare Pierce in the Hulu series "Tiny Beautiful Things," based on a book by 30-Across (2 wds.) |
| 45% | DEADLYCLASS | 11 | 2019 TV series developed by Rick Remender and Miles Orion which is based on a comic book series by Image Comics: 2 wds. |
| 43% | JOHNNYBRAVO | 11 | Muscular title character in a 1997-2004 Cartoon Network series: 2 wds. |
| 42% | WITCHSSISTER | 12 | First book in a fantasy series about black magic by Phyllis Reynolds Naylor (2 wds.) |
| 42% | SOUTHPARK | 9 | Animated Comedy Central series set in a small town in Colorado: 2 wds. |
| 42% | WHERESWALDO | 11 | Children's puzzle book series featuring a boy in a red and white hat (2 wds.) |
| 42% | RICHARDCASTLE | 13 | Sleuthing mystery writer played by Nathan Fillion on a current TV series: 2 wds. |
| 41% | MRT | 3 | Actor who played Baracus in "The A-Team" series: 2 wds. |
| 41% | ONTOUR | 6 | Performing concerts in a series of locations: 2 wds. |
| 41% | WHERESWALDO | 11 | Children's seek-and-find book series featuring a boy in a red and white hat (2 wds.) |
| 41% | QUEENSUGAR | 10 | OWN series based on a Natalie Baszile novel about a family farm in Louisiana (2 wds.) |
| 41% | STEVENUNIVERSE | 14 | Half-human, half-alien title character in a current Cartoon Network series: 2 wds. |
| 41% | JOHNNYENGLISH | 13 | Fictional spy portrayed by Rowan Atkinson in a series of parody films: 2 wds. |
| 41% | CAMJANSEN | 9 | Young female detective in books written by David A. Adler since 1980: 2 wds. |
| 41% | TEENWOLF | 8 | Current MTV drama based on a Michael J. Fox movie: 2 wds. |
| 40% | ERICMCCORMACK | 13 | 2001 Emmy winner, Outstanding Lead Actor in a Comedy Series (for "Will & Grace"): 2 wds. |
| 40% | CORKOCONNOR | 11 | Former small-town sheriff featured in a series of novels by William Kent Krueger, including "Iron Lake," 18-Across, and 29-Across (2 wds.) |
| 40% | FAMILYGUY | 9 | Animated series in which Mila Kunis voices a daughter named Meg: 2 wds. |
| 40% | ESSAYTEST | 9 | Exam that's sometimes written in a blue book: 2 wds. |
| 40% | IRONFIST | 8 | Finn Jones's Netflix series that's based on a Marvel comic: 2 wds. |
| 40% | JESSICAJONES | 12 | Krysten Ritter's Netflix series that's based on a Marvel comic: 2 wds. |
| 40% | LUKECAGE | 8 | Mike Colter's Netflix series that's based on a Marvel comic: 2 wds. |
| 40% | DONLARSEN | 9 | Yankees pitcher who threw a perfect game in the 1956 World Series: 2 wds. |
| 40% | THEOC | 5 | 2003-2007 Adam Brody TV series based in Southern California: 2 wds. |