| 100% | IAIN | 4 | Armitage who plays the title role on "Young Sheldon" |
| 68% | ALAN | 4 | Ritchson who plays the title role on "Reacher" |
| 68% | ELBA | 4 | Actor who played the title role on “Luther” |
| 68% | TOM | 3 | Actor Ellis who plays the title role on "Lucifer" |
| 68% | ALAN | 4 | Actor Ritchson who plays the title role on "Reacher" |
| 67% | LIEV | 4 | Actor Schreiber who plays the title role on "Ray Donovan" |
| 67% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 67% | KENNEDYMCMANN | 13 | Actress who plays the title role on "Nancy Drew": 2 wds. |
| 67% | RENEE | 5 | Zellweger who played the title role on "The Thing About Pam" |
| 67% | LORNA | 5 | Patterson who played the title role on TV's "Private Benjamin" |
| 67% | MAMIE | 5 | Gummer who played the title role on "Emily Owens, M.D." |
| 66% | CRAIGTNELSON | 12 | "Parenthood" actor who plays the title role on 60-Across (3 wds.) |
| 66% | ARMITAGE | 8 | Child actor Iain who plays the title role in "The Big Bang Theory" spin-off "Young Sheldon" |
| 66% | PATRICKSTEWART | 14 | "X-Men" actor who plays the title role on 50-Across (2 wds.) |
| 65% | ALANRITCHSON | 12 | "Titans" actor who plays the title role on the Amazon series "Reacher" (2 wds.) |
| 65% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 65% | NABORS | 6 | Actor Jim who played the title role on "Gomer Pyle, U.S.M.C." |
| 64% | BILLHADER | 9 | Former "Saturday Night Live" cast member who plays the title role on 4-Across (2 wds.) |
| 64% | MATTHEWRHYS | 11 | "The Americans" actor who plays the title role on "Perry Mason" (2 wds.) |
| 63% | DALE | 4 | Jim —, comic actor who played the title role in 1992 film Carry on Columbus |
| 59% | CARRIEPRESTON | 13 | "The Good Wife" actress who plays the title role on the CBS spin-off of "The Good Wife," "Elsbeth" (2 wds.) |
| 57% | IAIN | 4 | Actor Armitage who plays Sheldon Cooper on "Young Sheldon" |
| 56% | NATE | 4 | Actor who plays the title role in "Castle" |
| 56% | RICKMAN | 7 | Alan who played the title role in "Rasputin" |
| 56% | STONE | 5 | Emma who played the title role in "Cruella" |
| 56% | PATTINSON | 9 | Robert who plays the title role in 22 Across |
| 56% | ASTIN | 5 | Sean who played the title role in "Rudy," 1993 |
| 56% | ASA | 3 | Actor Butterfield who played the title role in "Hugo" |
| 56% | DORISDAY | 8 | Singer who played the title role in "Calamity Jane" |
| 56% | OSHEA | 5 | Michael who played the title role in "Jack London" |