| 100% | GUION | 5 | Astronaut ___ Bluford, the first African-American in space |
| 75% | MAE | 3 | Astronaut Jemison who was the first African-American woman in space |
| 72% | MAE | 3 | ___ Jemison, American astronaut who became the first African-American woman to travel to space in 1992 |
| 67% | MAE | 3 | Astronaut Jemison, the first African-American woman in NASA's training program |
| 66% | ALAN | 4 | Astronaut Shepard who was the first American in space |
| 66% | JEMISON | 7 | Mae, first African American woman in space |
| 66% | RIDE | 4 | Astronaut Sally who was the first American woman in space |
| 65% | MAEJEMISON | 10 | First African-American woman in space, aboard the space shuttle Endeavour in 1992: 2 wds. |
| 65% | ONEIL | 5 | Buck who became the first African American coach in the MLB |
| 64% | BUCK | 4 | O'Neil who was the first African American coach in the MLB |
| 64% | SALLYRIDE | 9 | She was the first American woman in Space |
| 63% | LLOYD | 5 | Earl ___, first African American to play in the NBA |
| 63% | MARIE | 5 | ___ Maynard Daly, the first African American woman to earn a Ph.D. in chemistry |
| 60% | SALLY | 5 | ___ Ride who was the first American woman in space |
| 60% | ALAN | 4 | Astronaut Shepard, first American in space |
| 60% | RIDE | 4 | She became the first American woman in space in 1983 |
| 59% | ELMO | 4 | Saint ___ Brady, first African American in the US to obtain a Ph.D. degree in chemistry (University of Illinois, 1916) |
| 59% | ETHELWATERS | 11 | Harlem Renaissance singer and actress who was the first African American to star in her own TV show: 2 wds. |
| 58% | HARRIS | 6 | Stayce, first African American to reach three star general rank in the US Air Force (2016) |
| 58% | SHEPARD | 7 | Alan who was the first American in space |
| 58% | FAYETTEVILLE | 12 | Where Senator Hiram Rhodes Revels, first African American to serve in the U.S. Congress, was born |
| 57% | LEEELDER | 8 | First African-American golfer to play in the Masters |
| 57% | MAE | 3 | ___ Jemison (first African American woman in space) |
| 57% | MAE | 3 | ___ Jemison, first African-American woman in space |
| 57% | MAE | 3 | Astronaut Jemison who was the first Black woman in space |
| 57% | OCHOA | 5 | Astronaut Ellen who was the first Hispanic woman in space |
| 56% | SALLY | 5 | ___ Ride, American astronaut who became the first American woman to fly in space in 1983 |
| 56% | KALPANA | 7 | ___ Chawla, American astronaut who became the first Indian woman to fly in space in 1997 |
| 56% | WARRENMOON | 10 | First African-American quarterback in the Pro Football Hall of Fame |
| 56% | ELDER | 5 | Lee __, first African-American to play in the Masters |